Shahid Beheshti University Journal of Sport and Exercise Physiology 2676-3710 15 1 2022 03 21 The effect of 8 weeks of continuous and high intensity interval swimming on chemerin levels in liver and visceral fat tissues and insulin resistance in male rats with metabolic syndrome The effect of 8 weeks of continuous and high intensity interval swimming on chemerin levels in liver and visceral fat tissues and insulin resistance in male rats with metabolic syndrome 33 44 101999 10.52547/joeppa.15.1.33 FA Hossein Zahraei Faculty of Sport Sciences, University of Birjand, Birjand, Iran Mehdi Mogharnasi Faculty of Sport Sciences, University of Birjand, Birjand, Iran 0000-0002-9351-5948 Mohammad Esmaeil Afzalpour Faculty of Sport Sciences, University of Birjand, Birjand, Iran 0000-0001-6468-8498 Hamed Fanaei Department of Physiology, Zahedan University of Medical Sciences, Zahedan, Iran Journal Article 2020 08 21 <strong>Purpose</strong>: The aim of the present study was to investigated the effect of 8 weeks of continuous and high intensity intermval swimming on chemerin levels in liver and visceral fat tissues and insulin resistance in rats with metabolic syndrome.<br /><strong>Methods</strong>: After induction of mice, to the metabolic syndrome, for the program performance, Rats (n = 32) randomly were divided into four groups (n = 8) including: standard or normal control, metabolic syndrome control, continuous swimming and high intensive interval swimming (with metabolic syndrome) groups. The continuous and high intensive interval swimmimg trained up to 65% and almost equivalent 100% of maximal oxygen uptake respectively. Blood and tissue (liver and visceral fat) variables were measured by ELISA method and the results were extracted using variance analysis test with repeated measurement.<br /><strong>Results</strong>: Continuous and high intensity interval swimming significantly reduced serum glucose level (P = 0.001), but the two types of performed exercises did not significantly changes in insulin resistance (P = 0.77) and liver tissue chemerin (P = 0.228); only high intensity interval swimming significantly reduced visceral adipose tissue (P = 0.0001) and rat weight (P = 0.029).<br /><strong>Conclusion</strong>: According to the results of the present study, both continuous and high intensive interval swimming exercises, can be considered as a preventive approach to improve insulin resistance and metabolic syndrome; but performing high intensive interval exercise will be more effective. More researches needed for difinite conclusion. <strong>Purpose</strong>: The aim of the present study was to investigated the effect of 8 weeks of continuous and high intensity intermval swimming on chemerin levels in liver and visceral fat tissues and insulin resistance in rats with metabolic syndrome.<br /><strong>Methods</strong>: After induction of mice, to the metabolic syndrome, for the program performance, Rats (n = 32) randomly were divided into four groups (n = 8) including: standard or normal control, metabolic syndrome control, continuous swimming and high intensive interval swimming (with metabolic syndrome) groups. The continuous and high intensive interval swimmimg trained up to 65% and almost equivalent 100% of maximal oxygen uptake respectively. Blood and tissue (liver and visceral fat) variables were measured by ELISA method and the results were extracted using variance analysis test with repeated measurement.<br /><strong>Results</strong>: Continuous and high intensity interval swimming significantly reduced serum glucose level (P = 0.001), but the two types of performed exercises did not significantly changes in insulin resistance (P = 0.77) and liver tissue chemerin (P = 0.228); only high intensity interval swimming significantly reduced visceral adipose tissue (P = 0.0001) and rat weight (P = 0.029).<br /><strong>Conclusion</strong>: According to the results of the present study, both continuous and high intensive interval swimming exercises, can be considered as a preventive approach to improve insulin resistance and metabolic syndrome; but performing high intensive interval exercise will be more effective. More researches needed for difinite conclusion. https://joeppa.sbu.ac.ir/article_101999_e608c3db747a17e3aebe8247977ddc3f.pdf