Shahid Beheshti University Journal of Sport and Exercise Physiology 2676-3710 15 4 2022 08 23 The effect of six weeks of combined training on the resting plasma level of Pentraxin-3 and Serum amyloid A in men with type-2 diabetes The effect of six weeks of combined training on the resting plasma level of Pentraxin-3 and Serum amyloid A in men with type-2 diabetes 1 10 102626 10.52547/joeppa.15.4.1 FA Hamidreza Haghgoo Department of Exercise Physiology , Faculty of Physical Education and Sport Sciences , University of Tehran, Tehran , Iran Siroos Choobineh Department of Exercise Physiology , Faculty of Physical Education and Sport Sciences , University of Tehran, Tehran , Iran 0000-0003-4466-0986 Parisa Pournemati Department of Exercise Physiology , Faculty of Physical Education and Sport Sciences , University of Tehran, Tehran , Iran Journal Article 2020 05 13 <strong>Background and Purpose:</strong> The aim of this study was to investigate the effect of combined exercise on resting levels of pentraxin3 (PTX3) and serum amyloid A (SAA) in the plasma of men with type-2 diabetes.<br /><strong>Materials and Methods:</strong> Twenty oen-athlete men with type-2 diabetes were randomly divided into control and training groups. Combined training was performed for six weeks. Training including 25-35 minutes of aerobic exercise with an intensity of 55-75% of maximum heart rate and five resistance movements involving large muscles in the upper and lower body Includes five movements: chest press, army press, squat, dead lift, dumbbell rowing with an intensity of 55-75% of a maximum repetition with a frequency of three times a week with the periorizing of resistance training on aerobic training . The intensity of aerobic exercise was measured with heart rate monitor and the intensity of resistance training was measured every two weeks with a maximum repetition test. For data analysis, dependent and independent t-test was used at the significant level of P ≤ 0.05.<br /><strong>Results:</strong> Examining the results of the study, it was found that the training contract reduced the SAA index (16.7%) and significantly changed it in the training group compared to the control group (P = 0.047 . However, there was no effect on resting SAA in the control group and a 2.2% increase in PTX3 in the training group was not significant (P = 0.474).<br /><strong>Conclusion:</strong> According to the results of the study and a significant decrease in inflammatory factor SAA and increase in PTX3, it can be concluded that six weeks of combined training affects the levels of these factors in men with type-2 diabetes and can probably reduce inflammation in these patients. <strong>Background and Purpose:</strong> The aim of this study was to investigate the effect of combined exercise on resting levels of pentraxin3 (PTX3) and serum amyloid A (SAA) in the plasma of men with type-2 diabetes.<br /><strong>Materials and Methods:</strong> Twenty oen-athlete men with type-2 diabetes were randomly divided into control and training groups. Combined training was performed for six weeks. Training including 25-35 minutes of aerobic exercise with an intensity of 55-75% of maximum heart rate and five resistance movements involving large muscles in the upper and lower body Includes five movements: chest press, army press, squat, dead lift, dumbbell rowing with an intensity of 55-75% of a maximum repetition with a frequency of three times a week with the periorizing of resistance training on aerobic training . The intensity of aerobic exercise was measured with heart rate monitor and the intensity of resistance training was measured every two weeks with a maximum repetition test. For data analysis, dependent and independent t-test was used at the significant level of P ≤ 0.05.<br /><strong>Results:</strong> Examining the results of the study, it was found that the training contract reduced the SAA index (16.7%) and significantly changed it in the training group compared to the control group (P = 0.047 . However, there was no effect on resting SAA in the control group and a 2.2% increase in PTX3 in the training group was not significant (P = 0.474).<br /><strong>Conclusion:</strong> According to the results of the study and a significant decrease in inflammatory factor SAA and increase in PTX3, it can be concluded that six weeks of combined training affects the levels of these factors in men with type-2 diabetes and can probably reduce inflammation in these patients. https://joeppa.sbu.ac.ir/article_102626_ca1c611b9b56977d060dddbb0cbec01d.pdf