مقایسه تاثیر تمرین هوازی در هنگام صبح و عصر بر شاخص‌های التهابی خطرزای قلبی- عروقی مردان چاق

نوع مقاله : علمی - پژوهشی

نویسندگان

داﻧﺸﮕﺎه ﻗﻢ،

چکیده

هدف: هدف مطالعه حاضر، مقایسه اثر12 هفته تمرین هوازی در هنگام صبح و عصر بر شاخص‌های التهابی خطرزای قلبی- عروقی در مردان چاق بود. روش‌شناسی: پژوهش حاضر از نوع شبه آزمایشی بود که بدین منظور40 مرد چاق غیر ورزشکار به صورت تصادفی در 4 گروه تمرین صبح عصر، کنترل صبح و عصر قرار گرفتند. گروه های تمرین صبح و عصر پروتکل تمرین هوازی دویدن را سه جلسه در هفته به مدت 12 هفته با شدت 75 تا 85 درصد حداکثر ضربان قلب انجام دادند که مدت دویدن در جلسه اول 15 دقیقه و هردو جلسه بصورت پله ای یک دقیقه به زمان دویدن افزوده شد تا اینکه زمان دویدن به 30 دقیقه افزایش یافت، در حالی که گروه‌های کنترل از انجام برنامه تمرینی در مدت زمان اجرای پژوهش منع شدند. مقدار 5 میلی لیتر خون سیاهرگی در آغاز دوره، هفته ششم و پایان هفته دوازدهم جهت سنجش پروتئین واکنش پذیر C، اینتر لوکین – 6 و فاکتور نکروز دهنده تومور آلفا از آزمودنی ها جمع اوری شد. تجزیه و تحلیل داده ها با استفاده از آزمون تحلیل واریانس عاملی4×3 بوسیله نر م‌افزار رایانه‌ای SPSS نسخه 15 با در نظر گرفتن سطح معنی‌داری پنج درصد(5%=α)انجام شد. نتایج: یافته ها نشان داد تمرین هوازی صبحگاهی و عصرگاهی موجب کاهش CRP،IL-6، در گروه‌های تجربی در مقایسه با گروه-های کنترل شد، همچنین مقادیر تولید شاخص‌های التهابی در عصر کمتر از صبح بود(میزان CRP در گروه تمرین عصرگاهی در هفته اول ،ششم و دوازدهم به ترتیب 1/17، 5/10، 87/18 درصد و میزان IL-6 نیز به ترتیب 5/21، 74/16، 32/25 درصد کمتر از گروه تمرین صبحگاهی بود). سطح فاکتور نکروز دهنده تومور آلفا پس از 6 و 12 هفته تمرین در گروه‌های تجربی در مقایسه با گروه‌های کنترل کاهش نشان می‌داد و لی این میزان تغییرات از نظر آماری معنی‌دار نبود.

کلیدواژه‌ها

عنوان مقاله [English]

Comparison The effects of morning and evening Aerobic training on the Inflammatory Markers of Cardiovascular Disease Risk in obes men

چکیده [English]


Purpose: The inflammatory markers cause changes in body composition and endocrine activity and lead to
cardiovascular disease and diabetes. The aim of present study was to determine the comparison the effects of 12
weeks of morning and evening aerobic training . Method: this study was of type Quasi – experiments, 40 nonathletes,
obese men were randomly allocated to four groups of morning and evening aerobic training and morning
and evening control. Morning and evening training groups performed the aerobic training protocol three sessions per
week for 12 weeks with 75 to 85 percent of maximal heart rate and 15 minutes training per session. The training
time was increasingly added 1 minute every two session until the training time reached to 30 minutes .while the
control groups were denied doing training programs during the research period. Blood samples (5 cc) were taken
from the participants at the beginning of the period, week 6 and end of week 12 in order to measure C-reactive
protein (CRP), interlukin-6 (IL-6) and tumor necrosis factor-alpha (TNF- α). Statistical analysis of the data was
performed using the 4× 3 factorial ANOVA with statistical process was done using SPSS software, version 15, and
the significance level was considered P<0.05Results: The results showed that morning and evening aerobic training
decreased CRP and IL-6 in the experimental groups compared with the control ones. Also, the amount of produced
inflammatory markers was less in the evening than in the morning (in the evening training group, the amount of
CRP was 17.1%, 10.5% and 18.87% in week 1, week 6 and week12 and the amount of IL-6 was respectively 21.5%,
16.74% and 25.32% lower than that of the morning training group). level of TNF-α decreased in the experimental
group mor than control group after 6 and 12 weeks of training, Although this change was not
significant..Conclusion: According to the results of this study, it was determined that different times of the day
influence the compatibility of inflammatory markers caused by aerobic training and these markers show more
reduction in the evening. Therefore, it is recommended to young obese men to do exercises in the evening rather
than morning.

کلیدواژه‌ها [English]

  • Aerobic training
  • Morning
  • Evening
  • inflammatory markers
  • Coronary heart disease
  • obese me

مراجع

  1. منابع
  2. Hammett CJ. Effect of six months, exercise
  3. training on C-reactive protein levels in healthy
  4. elderly subjects. AM coll cardiol. 2004;44.
  5. Abramson JL, Vaccarino V. Relationship
  6. between physical activity and inflammation
  7. مقایسه تاثیر تمرین هوازی در هنگام صبح و عصر بر شاخصهای التهابی خطرزای قلبی- عروقی مردان چاق 776
  8. among apparently healthy middle-aged and
  9. older US adults. Arch Intern Med. 2002 Jun
  10. ;162(11):1286-92.
  11. Witkkowska AM. Soluble ICAM-1: A marker
  12. of vaskular inflammation and lifestily Cytokine.
  13. ;31.
  14. barbara jn. exercise,weight loss,andeffect on
  15. inflammation. curr cardio risk rep. 2010;4.
  16. Beavers KM, Hsu FC, Isom S, Kritchevsky SB,
  17. Church T, Goodpaster B, et al. Long-term
  18. physical activity and inflammatory biomarkers
  19. in older adults. Med Sci Sports Exerc. 2010
  20. Dec;42(12):2189-96.
  21. Kohut ML, McCann DA, Russell DW, Konopka
  22. DN, Cunnick JE, Franke WD, et al. Aerobic
  23. exercise, but not flexibility/resistance exercise,
  24. reduces serum IL-18, CRP, and IL-6
  25. independent of beta-blockers, BMI, and
  26. psychosocial factors in older adults. Brain Behav
  27. Immun. 2006 May;20(3):201-9.
  28. Nicklas BJ, Hsu FC, Brinkley TJ, Church T,
  29. Goodpaster BH, Kritchevsky SB, et al. Exercise
  30. training and plasma C-reactive protein and
  31. interleukin-6 in elderly people. J Am Geriatr
  32. Soc. 2008 Nov;56(11):2045-52.
  33. Kadoglou NP, Iliadis F, Angelopoulou N, Perrea
  34. D ,Ampatzidis G, Liapis CD, et al. The antiinflammatory
  35. effects of exercise training in
  36. patients with type 2 diabetes mellitus. Eur J
  37. Cardiovasc Prev Rehabil. 2007 Dec;14(6):837-
  38.  
  39. Walther C, Mobius-Winkler S, Linke A, Bruegel
  40. M, Thiery J, Schuler G ,et al. Regular exercise
  41. training compared with percutaneous
  42. intervention leads to a reduction of inflammatory
  43. markers and cardiovascular events in patients
  44. with coronary artery disease. Eur J Cardiovasc
  45. Prev Rehabil. 2008 Feb;15(1):107-12.
  46. Campbell PT ,Campbell KL, Wener MH, Wood
  47. BL, Potter JD, McTiernan A, et al. A yearlong
  48. exercise intervention decreases CRP among
  49. obese postmenopausal women. Med Sci Sports
  50. Exerc. 2009 Aug;41(8):1533-9.
  51. Christiansen T, Paulsen SK, Bruun JM, Pedersen
  52. SB, Richelsen B. Exercise training versus dietinduced
  53. weight-loss on metabolic risk factors
  54. and inflammatory markers in obese subjects: a
  55. -week randomized intervention study. Am J
  56. Physiol Endocrinol Metab. 2010
  57. Apr;298(4):E824-31.
  58. Fairey AS, Courneya KS, Field CJ, Bell GJ,
  59. Jones LW, Martin BS, et al. Effect of exercise
  60. training on C-reactive protein in postmenopausal
  61. breast cancer survivors: a randomized controlled
  62. trial. Brain Behav Immun. 2005 Sep;19(5):381-
  63.  
  64. Arsenault BJ. effect of exercise training on
  65. cardiometabolic risk markers among sedentry,
  66. but metabolically healthy overweight or obese
  67. post-menipausal women with elevated blood
  68. ptessure. Atherosclerosis. 2009;207.
  69. Pledge D, Grosset JF, Onambele-Pearson GL. Is
  70. there a morning-to-evening difference in the
  71. acute IL-6 and cortisol responses to resistance
  72. exercise? Cytokine. 2011 May 30.
  73. Piccionea G. The effect of physical exercise on
  74. the daily rhythm of platelet aggregation and
  75. body temperature in horses. The Veterinary
  76. Journal. 2007;176:216.
  77. Aldmir H, Kilic,H. The effect of time of day
  78. and exercise on platelet functions and platelet–
  79. neutrophil aggregates in healthy male subjects.
  80. ;280:119–124, . Molecular and Cellular
  81. Biochemistry. 2005;280.
  82. Olejnik sf. Planning education research.
  83. Determining the necessery sample size. journal
  84. of experimental educacion. 1984;53:40-8.
  85. H WM. Nutrition for Health, Fitness and sport.
  86. MC craw Hill. Edition S, editor2002.
  87. Tanaka H. MKD, Seals D.R. Predicted Maximal
  88. Heart Rate Revisited. AM Coll Cardiol 2001
  89. Jan. 2001;37(1):153-6.
  90. Ryan AS. Reductions in plasma cytokine levels
  91. with weight loss improve insulin sensitivity in
  92. overweight and obese postmenopausal woman.
  93. Diabetes care. 2004;27(7):1699-705.
  94. Bruunsgaard H. Physical activity and
  95. modulation of systemic low-level inflammation.
  96. J Leukoc Biol. 2005 Oct;78(4):819-35.
  97. Hamedinia RM. The Effect of Aerobic Training
  98. on Inflammatory Markers of Cardiovascular
  99. Disease Risk in Obese Men. World Journal of
  100. Sport Sciences. 2009;2(1.(
  101. batista jr. anti-inflammatory effect of physical
  102. training in heart failur:role of TNF-a and IL-10.
  103. Arq Bras Cardiol. [Review Article]2008;93(6).
  104. Chaikate S, Harnroongroj T, Chantaranipapong
  105. Y, Puduang S, Mahaisiriyodom A,
  106. Viroonudomphol D, et al. C-reactive protein,
  107. محسن عصارزاده نوش آبادی و همکاران
  108. interleukin-6, and tumor necrosis factor-alpha
  109. levels in overweight and healthy adults.
  110. Southeast Asian J Trop Med Public Health. 2006
  111. Mar;37(2):374-81.
  112. Mattusch F, Dufaux B, Heine O, Mertens I, Rost
  113. R. Reduction of the plasma concentration of Creactive
  114. protein following nine months of
  115. endurance training. Int J Sports Med. 2000
  116. Jan;21(1):21-4.
  117. Smith JK, Dykes R, Douglas JE, Krishnaswamy
  118. G, Berk S. Long-term exercise and atherogenic
  119. activity of blood mononuclear cells in persons at
  120. risk of developing ischemic heart disease.
  121. JAMA. 1999 May 12;281(18):1722-7.
  122. Straczkowski M, Dzienis-Straczkowska S,
  123. Stepien A, Kowalska I, Szelachowska M,
  124. Kinalska I. Plasma interleukin-8 concentrations
  125. are increased in obese subjects and related to fat
  126. mass and tumor necrosis factor-alpha system. J
  127. Clin Endocrinol Metab. 2002 Oct;87(10):4602-6.
  128. Bruun JM, Helge JW, Richelsen B, Stallknecht
  129. B. Diet and exercise reduce low-grade
  130. inflammation and macrophage infiltration in
  131. adipose tissue but not in skeletal muscle in
  132. severely obese subjects. Am J Physiol
  133. Endocrinol Metab. 2006 May;290(5):E961-7.
  134. Forsythe LK, Wallace JM, Livingstone MB.
  135. Obesity and inflammation: the effects of weight
  136. loss. Nutr Res Rev. 2008 Dec;21(2):117-33.
  137. Church TS, Barlow CE, Earnest CP, Kampert
  138. JB, Priest EL, Blair SN. Associations between
  139. cardiorespiratory fitness and C-reactive protein
  140. in men. Arterioscler Thromb Vasc Biol. 2002
  141. Nov 1;22(11):1869-76.
  142. Kim ES, Im JA, Kim KC, Park JH, Suh SH,
  143. Kang ES, et al. Improved insulin sensitivity and
  144. adiponectin level after exercise training in obese
  145. Korean youth. Obesity (Silver Spring). 2007
  146. Dec;15(12):3023-30.
  147. Dietrich M, Jialal I. The effect of weight loss on
  148. a stable biomarker of inflammation, C-reactive
  149. protein. Nutr Rev. 2005 Jan;63(1):22-8.
  150. You T, Nicklas BJ. Effects of exercise on
  151. adipokines and the metabolic syndrome. Curr
  152. Diab Rep. 2008 Feb;8(1):7-11.
  153. Kirk EA, Sagawa ZK, McDonald TO, O'Brien
  154. KD, Heinecke JW. Monocyte chemoattractant
  155. protein deficiency fails to restrain macrophage
  156. infiltration into adipose tissue [corrected].
  157. Diabetes. 2008 May;57(5):1254-61.
  158. Ziccardi P, Nappo F, Giugliano G, Esposito K,
  159. Marfella R, Cioffi M, et al. Reduction of
  160. inflammatory cytokine concentrations and
  161. improvement of endothelial functions in obese
  162. women after weight loss over one year.
  163. Circulation. 2002 Feb 19;105(7):804-9.
  164. Ding Y, Li J, Luan X, Ding YH, Lai Q, Rafols
  165. JA, et al. Exercise pre-conditioning reduces
  166. brain damage in ischemic rats that may be
  167. associated with regional angiogenesis and
  168. cellular overexpression of neurotrophin.
  169. Neuroscience. 2004;124(3):583-91

فایل ها

سابقه مقاله

  • تاریخ دریافت: 27 اردیبهشت 1394
  • تاریخ بازنگری: 29 خرداد 1403
  • تاریخ پذیرش: 11 دی 1399
  • تاریخ اولین انتشار: 11 دی 1399
  • تاریخ انتشار: 01 اردیبهشت 1391

هم رسانی

ارجاع به این مقاله

آمار