مقایسه سه شیوه تمرین ورزشی بر غلظت پروتئین واکنش‌دهندهC و گلبول‌های سفید خونی در بیماران دیابتی نوع2

نوع مقاله : علمی - پژوهشی

نویسندگان

1 دانشیار فیزیولوژی ورزشی دانشگاه بوعلی همدان

2 کارشناسی ارشد فیزیولوژی ورزش دانشگاه بوعلی همدان

چکیده

چکیدههدف: دیابت از جمله بیماری‌هایی است که باعث کاهش عملکرد سیستم دفاعی بدن در برابر عفونت‌ها می‌شود. از گونه میانجی‌های التهابی که به‌دنبال فعل‌و‌انفعالات التهاب در کنار گلبول‌های سفید ترشح می‌شود، پروتئین واکنش‌دهنده(CRP) C  است، که نشانگر حساسی برای التهاب سیستمیک محسوب می‌شود. تمرین منظم با کنترل سوخت و ساز در دیابتی‌ها باعث کنترل قند خون می‌شود و به‌دنبال آن پاسخ دفاعی بدن را افزایش می‌دهد. به‌همین منظور این مطالعه به‌مقایسه اثر سه شیوه تمرین ورزشی بر CRPو گلبول‌های سفید در بیماران دیابتی نوع II  طراحی شده است. روش شناسی: در این پژوهش، 52 بیمار مرد دیابتی نوعII (65-40 سال) بطور تصادفی به 4 گروه تمرینی هوازی، مقاومتی، ترکیبی و کنترل تقسیم شدند. در هر گروه 13 نفر قرار گرفت. تمرینات سه جلسه در هفته، هر جلسه 60 دقیقه بمدت 10هفته بطول انجامید. hs-CRP  به روش الایزا و شمارش عناصر WBC در ابتدا و پایان مطالعه اندازه‌گیری شد.  نتایج: یافته‌ها تحقیق نشان داد که تمرینات هوازی بطور معنی‌داری باعث کاهشhs-CRP و افزایش مونوسیت‌ها شد. همچنین تمرینات ترکیبی نیز باعث کاهش سطح CRP و نوتروفیل‌ها و افزایش مونوسیت‌ها و لنفوسیت‌ها شد. کاهش CRP در گروه ترکیبی نسبت به گروه هوازی بتنهایی بارزتر بود ولی در عناصرWBC تفاوتی نداشت. بحث و نتیجه‌گیری: براساس یافته‌های پژوهش تجویز تمرینات ورزشی هوازی و بویژه ترکیبی می‌تواند روش مناسب برای جلوگیری از بروز عوارض دیابت نوع IIباشد.   

کلیدواژه‌ها

عنوان مقاله [English]

Comparison of three exercise training method on plasma CRP levels and WBC in patients with type II diabetes

چکیده [English]



Purpose Diabetes is a disease that causes a decrease in the function of the immune system of the body against infections.
One of the inflammatory mediators, secreted along the white corpuscles after the interactions of inflammation, is CRP,
which is a sensitive marker for systemic inflammation. Regular exercise with controlling metabolism in diabetes controls
the blood glucose level and subsequently increases the immune response of body. For this purpose, this study has been
designed to compare three different ways of training on CRP and WBC levels in type 2 diabetic patients. Methods: 52
patients with type 2 diabetes (40-65 years old) were randomly divided into four groups: aerobic training, resistance,
combined (aerobic and resistance) and control groups and each group consisted of 13 subjects. The exercises were done 3
times a week for 60 minutes each session and lasted for 10 weeks. The WBC counts and high-sensitivity CRP (hs-CRP) at
baseline and at the end of the study were measured by ELISA. Results: The research findings showed significant
reduction in hs-CRP and increased MONO, aerobic exercise group and decrease in CRP and NEUT levels and increase in
MONO and LYM were seen in the combination group. CRP in the combination group was significantly higher than
aerobic alone, but no difference in WBC groups was noticed. Conclusions: According to the findings, the research
prescribes aerobic exercise training can be a particularly suitable compound to prevent complications of type 2 diabetes.

کلیدواژه‌ها [English]

  • C-reactive protein
  • white blood cell
  • exercise training
  • type 2 diabetes

مراجع

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سابقه مقاله

  • تاریخ دریافت: 08 اسفند 1395
  • تاریخ بازنگری: 22 خرداد 1403
  • تاریخ پذیرش: 11 دی 1399
  • تاریخ اولین انتشار: 11 دی 1399
  • تاریخ انتشار: 01 آذر 1395

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