تاثیر یک جلسه فعالیت ورزشی تناوبی هوازی بر سطوح سرمی اسپکسین در مردان جوان فعال

نوع مقاله : علمی - پژوهشی

نویسندگان

1 دانشگاه مازندران

2 دانشگاه پیام نور گنبد کاووس

3 دانشگاه آزاد چالوس

چکیده

هدف: اسپکسین پپتید جدیدی است که در تنظیم رفتار تغذیه، وزن، متابولیسم انرژی و برداشت اسیدهای چرب به درون سلول­های چربی نقش دارد. هدف از مطالعه حاضر، بررسی تأثیر یک جلسه فعالیت­ورزشی تناوبی هوازی بر سطوح­سرمی­اسپکسین بود. روش­: یازده مرد جوان ­فعال (سن 3.63±24.00 سال، شاخص­­توده­­بدنی 2.00±22.98 کیلوگرم­بر­مترمربع) در این مطالعه شرکت نمودند. فعالیت­ورزشی شامل 2 سری (10ثانیه×6) رکاب­زدن با حداکثر سرعت و 10 دقیقه استراحت فعال (رکاب­زدن با شدت %75-%65 حداکثرضربان­قلب) بود. نمونه­های­خونی در وضعیت­ناشتا، قبل (30 دقیقه بعداز صرف­صبحانه حدود 365 کیلوکالری)، بلافاصله، 15، 30 و 45 دقیقه بعد از فعالیت ورزشی جمع­آوری شد. از آنالیز واریانس با اندازه­گیری­های مکرر و آزمون­تعقیبی بونفرونی برای بررسی تغییرات متغیرها در بازه­های زمانی مختلف و از ضریب­همبستگی پیرسون برای بررسی ارتباط بین متغیرها استفاده شد. یافته­ها: باوجود تغییر سطوح ­برخی از متابولیت­ها نظیر گلوکز، انسولین، لاکتات، TG و LDL-C در این پژوهش، تغییر معنی­داری در سطوح­ سرمی ­اسپکسین در هیچ یک از بازه­های زمانی اندازه­گیری شده، مشاهده­نشد (0.05p>). در حالت ناشتا و بلافاصله پس از فعالیت ­ورزشی، ارتباط معنی­داری بین سطوح اسپکسین و سایر متابولیت­ها یافت نشد (0.05p>) اما در 30 دقیقه پس از صرف صبحانه، سطوح­اسپکسین همبستگی منفی و معنی­داری با TG (0.032=p و 0.645- =r) و در طول دوره ریکاوری همبستگی مثبت و معنی­داری با HDL-C (0.041=p و 0.357+ =r) و همبستگی منفی و معنی­داری با انسولین داشت (0.023=p و 0.672- =r). نتیجه­گیری: به ­نظر می­رسد که تعادل ­منفی ­انرژی ناشی از یک جلسه فعالیت­ورزشی تناوبی هوازی، احتمالاً برای القای تغییر سطوح­ سرمی ­اسپکسین کافی نبوده­است.

کلیدواژه‌ها

عنوان مقاله [English]

The Effect of Single session of Aerobic Interval Exercise on Serum Spexin Levels in Active Young Men

چکیده [English]

Abstract
Aim: Spexin is a novel peptide which plays a role in the regulation of feeding behavior, body weight, energy metabolism, and long-chain fatty acid uptake into adipocytes. The aim of the current study was investigate the effect of single session of aerobic interval exercise on serum Spexin levels. Methods: Eleven active young men (aged 24±3.63 years, BMI 22.98±2 kg/m2) volunteered for this study. Acute exercise protocol comprising 2 series of 6×10 s sprinting cycling with maximal effort and 10 min active rest (cycling with intensity 65%–75% HRmax). Blood samples were obtained at fasting state, pre-exercise (30 min after breakfast ~365 kcal), immediately after, and 15, 30, and 45 min after exercise. The repeated measures of ANOVA and Bonferroni post-hoc test used to evaluate changes of parameters in the different times. The relationship between variables was assessed using the Pearson correlation coefficient. Results: Despite the changing levels of some metabolites such as glucose, insulin, lactate, TG and LDL-C in this study, spexin levels did not change significantly in any time courses of this study (p>0.05). At fasting state and post-exercise, spexin levels not correlated with other metabolites (p>0.05) but in 30 minutes after breakfast (pre-exercise) negatively correlated with TG (r= -0.645, p=0.032) and during the recovery period, positively correlated with HDL-C (r= +0.357, p=0.041) and negatively correlated with insulin (r= -0.672, p=0.023). Conclusion: It seems that acute exercise-induced negative energy balance in this study may not be sufficient to induce changes in Spexin serum levels.

کلیدواژه‌ها [English]

  • Spexin
  • Aerobic Interval Exercise
  • Active Young Men

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سابقه مقاله

  • تاریخ دریافت: 02 شهریور 1395
  • تاریخ بازنگری: 30 خرداد 1403
  • تاریخ پذیرش: 11 دی 1399
  • تاریخ اولین انتشار: 11 دی 1399
  • تاریخ انتشار: 01 آذر 1396

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