Journal of Sport and Exercise Physiology

Journal of Sport and Exercise Physiology

Effect of Endurance Training on miR-196a and miR-133a Expression in Subcutaneous White Adipose Tissue of Wistar Rats

Document Type : original article

Authors
Saeed Daneshyar 1
Mohammad Reza Kordi 2
Mehdi Kadivar 3
Samane Afshari 4
1 Department of Physical Education, University of Ayatollah Alozma Boroujerdi
2 Department of exercise physiology, Faculty of Physical Education and Sports Sciences,Tehran University
3 Department of Biochemistry, Pasteur Institute of Iran
4 Department of exercise physiology; Faculty of Physical Education and Sports Sciences, Tehran University
10.52547/joeppa.12.1.1
Abstract
Purpose: The aim of current study was to investigate the effect of endurance training on expression of miR-196a and miR-133a in subcutaneous white adipose tissue (WAT).
Methods: 16 wistar rats were divided into two groups included: 1) Control (n=8) and 2) Endurance Training (n=8). The subjects of training group underwent continues endurance training on treadmill for eight weeks. To measure of gene expression were used the Real Time (RT) –PCR method.
Results: Data showed that gene expression of UCP1 was significantly higher in trained group than control (P0.05).
Conclusions: The results of this study showed that the endurance training did not change the expression of miR-196a and miR-133a in subcutaneous WAT, indicating that the endurance training-induced the increase of UCP1 expression did not relate to change of miR-196a and miR-133a expression.
Keywords
endurance training
miR 196a
miR 133a
White adipose tissue
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  • Receive Date 14 May 2017
  • Revise Date 07 February 2021
  • Accept Date 31 December 2020
  • First Publish Date 31 December 2020
  • Publish Date 20 February 2019