The effect of 6 weeks Tai chi training on TNF-α, BDNF serum levels and cognitive and physical function in women with stroke

Document Type : original article

Abstract

The aim of this study was to determine the effect of Tai Chi training on TNF-α, BDNF serum levels and cognitive and physical function in women with stroke. 20 women in Qom city with stroke (mean age: 68/80±3/55y, weight: 68/41±14/00 kg and body mass index: 26/33± 5/15kg/m2) voluntarily were divided randomly into Tai Chi group (10 patients) and control group (10 patients). Serum BDNF and TNF-α were analyzed by using an ELISA kits in pretest and post-test. Cognitive function were assessed by the Mini-Mental State Examination (MMSE). Also pretest and post-test measurements were recorded for the timed up-and-go test. Tai Chi group trained 6 weeks, three times per week for 60 minute(consisted of a 10-minute warm-up period, 40-minutes simplified Tai Chi exercises performed, and a 10-minute cool-down period). Data were analyzed using the independent samples T-test and paired samples T-test. Tai Chi group showed a significant improvement in serum TNF-α and dynamic balance (p≤0.05). Despite the increase in serum BDNF and improvement cognitive function, no significant differences were observed between the two groups. Therefore the findings of this study suggest that Tai Chi training as a low intensity and simple training can improve women balance and inflammatory status with stroke.

Keywords

References

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History

  • Receive Date: 27 December 2015
  • Revise Date: 19 June 2024
  • Accept Date: 31 December 2020
  • First Publish Date: 31 December 2020
  • Publish Date: 22 May 2017

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