Acute and chronic effect of high-intensity interval training in nutral and hot environment on serum BDNF levels in healthy men

Taherirad, Elnaz; Rajabi, Hamid

doi:10.48308/joeppa.2018.98901

Acute and chronic effect of high-intensity interval training in nutral and hot environment on serum BDNF levels in healthy men

Document Type : original article

Authors

Faculty of Physical Education and Sport Science, Kharazmi University, Tehran, Iran

10.48308/joeppa.2018.98901

Abstract

Purpose: The purpose of this study was to determine the effect of high intensity interval training in
temperate and warm environment on serum BDNF in healthy men.
Methods: In this research, 24 healthy male students according to vVo2max estimation divided to 3 groups,
training in the warm environment (n=8), training in the temperate environment (n=8) and control (n=8)
categorized as matched. Subjects of experimental group were trained 12 sessions for two weeks. Each session
included 5 set of 150 seconds running on treadmill with %85-90 of vVo2max with 150 seconds active recovery
between each set with 50 percent of vVo2max. Serum BDNF was assessed using ELISA kits and the data were
analyzed by one-way ANOVA.
Results: The results show that one session high intensity interval activity in warm (p=0.018) and temperate
(p=0.045) environment induce significant increment in serum BDNF, However between training group,
significant difference was not observed (p=0.262). Furthermore two weeks of high intensity interval training
in warm (p=0.001) and temperate (p=0.012) environment resulted in significant increment in serum BDNF,
also two weeks of training on the level of BDNF not produce significant difference between training and
control groups (p=0.267).
Conclusions: It seems that high intensity interval training regardless of whether in temperate or warm
environment increases the level of BDNF.

Keywords

References

Duman RS .Synaptic plasticity and mood
disorders. Molecular psychiatry. 2002; 7Suppl
1:S29-34.
2. Nakagawa T, Tsuchida A, Itakura Y, Nonomura
T, Ono M, Hirota F, et al. Brain-derived
neurotrophic factor regulates glucose metabolism by modulating energy balance in
diabetic mice. Diabetes. 2000; 49(3): 436-44.
3. Ernfors P, Kucera J, Lee K, Loring J, Jaenisch R.
Studies on the physiological role of brainderived neurotrophic factor and
neurotrophin- 3in knockout mice. The
International journal of developmental
biology. 1995; 39(5): 799-627.
4. Pan W, Banks WA, Fasold MB, Bluth J, Kastin
AJ. Transport of brain-derived neurotrophic
factor across the blood-brain barrier.
Neuropharmacology. 1998; 37(12): 61-1553.
5. Karege F, Schwald M, Cisse M. Postnatal
developmental profile of brain-derived
neurotrophic factor in rat brain and platelets.
Neuroscience letters. 2002; 328(3): 4-261.
6. Smith MA, Makino S, Kvetnansky R, Post RM.
Effects of stress on neurotrophic factor
expression in the rat brain. Annals of the New
York Academy of Sciences. 1995; 9: 771-234.
7. Kramer AF, Hahn S, Cohen NJ, Banich MT,
McAuley E, Harrison CR, et al. Ageing, fitness
and neurocognitive function. Nature. 1999;
400(6743): 9-418.
8. Vaynman S, Gomez‐Pinilla F. Revenge of the
“sit”: how lifestyle impacts neuronal and
cognitive health through molecular systems
that interface energy metabolism with
neuronal plasticity. Journal of neuroscience
research. 2006; 84(4): 715-699.
9. Schmolesky MT, Webb DL, Hansen RA. The
effects of aerobic exercise intensity and duration
on levels of brain-derived neurotrophic factor in
healthy men. Journal of sports science &
medicine. 2013; 12(3): 11-522.
10. Ferris LT, Williams JS, Shen C-L. The effect of
acute exercise on serum brain-derived
neurotrophic factor levels and cognitive
function. Medicine and science in sports and
exercise. 2007; 39(4): 34-728.
11. Soya H, Nakamura T, Deocaris CC, Kimpara A,
Iimura M, Fujikawa T, et al. BDNF induction
with mild exercise in the rat hippocampus.
Biochemical and biophysical research
communications. 2007; 358(4): 961-967.
12. Satarifard S, Gaeini A, Choobineh C. Changes in
Blood Cortisol and Lactate Levels in Athletes
after One Exercise Session in Cold, Warm and
Natural Environments. Iranian Journal of
Endocrinology & Metabolism. 2012; 14(2): 169-177.
13. Goekint M, Roelands B, Heyman E, Njemini R,
Meeusen R. Influence of citalopram and
environmental temperature on exerciseinduced changes in BDNF. Neuroscience
letters. 2011; 494(2): 150-40.
14. Trost SG, Owen N, Bauman AE ,Sallis JF, Brown
W. Correlates of adults' participation in physical
activity: review and update. Medicine & Science
in Sports & Exercise2002.; 12: 1996-2001.
15. Godin G, Desharnais R, Valois P, Lepage L,
Jobin J, Bradet R. Differences in perceived
barriers to exercise between high and low
intenders: observations among different
populations. American Journal of Health
Promotion1994. ; 8(4): 385-279.
16. Gibala MJ, McGee SL. Metabolic adaptations
to short-term high-intensity interval training: a
little pain for a lot of gain? Exercise and sport
sciences reviews. 2008; 36(2): 63-58.
17. Laursen PB .Training for intense exercise
performance: high-intensity or high-volume
training? Scandinavian journal of medicine &
science in sports. 2010; 20(1): 10-2.
18. Little JP, Safdar A, Wilkin GP, Tarnopolsky MA,
Gibala MJ. A practical model of low-volume
high-intensity interval training induce mitochondrial biogenesis in human skeletal
muscle: potential mechanisms. The Journal of
physiology. 2010; 588(6): 22-1011.
19. Babak F, Gharakhanlou R, Bayati M,
Aghaalinezhad H, Mohebbi F. Effect of
intensity interval training on aerobic,
anaerobic and hematological performance
indices on athletes. Sport and Exercise
physiology. 1390; 16(9): 25-40.
20. Bartlett JD, Close GL, MacLaren DP, Gregson
W, Drust B, Morton JP. High-intensity interval
running is perceived to be more enjoyable
than moderate-intensity continuous exercise:
implications for exercise adherence. Journal of
sports sciences. 2011; 29(6): 53-547.
21. Barzegar H, Vasdi E, Borjianfard M. The effects
of different exercise training on Brain-derived
neutrophic factor in rats. Journal of Tehran
biological sciences. 1394; 6(23): 1-9.
22. Déry N, Pilgrim M, Gibala M, Gillen J ,
Wojtowicz JM, MacQueen G, et al. Adult
hippocampal neurogenesis reduces memory
interference in humans: opposing effects of
aerobic exercise and depression. Frontiers in
neuroscience. 2013; 7(14): 7-56.
23. Schmidt-Kassow M, Schädle S ,Otterbein S,
Thiel C, Doehring A, Lötsch J, et al. Kinetics of
serum brain-derived neurotrophic factor
following low-intensity versus high-intensity
exercise in men and women. Neuroreport.
2012; 23(15): 889-701.
24. De Lisio M, Phan N, Boreham DR, Parise G.
Exercise-induced protection of bone marrow
cells following exposure to radiation. Applied
Physiology, Nutrition, and Metabolism. 2010;
36(1): 7-80.
25. Watson P, Shirreffs SM, Maughan RJ. Bloodbrain barrier integrity may be threatened by
exercise in a warm environment. American
Journal of Physiology-Regulatory, Integrative
and Comparative Physiology. 2005; 288(6):
1689-94.
26. Garcia C, Chen M, Garza A, Cotman C, RussoNeustadt A. The influence of specific
noradrenergic and serotonergic lesions on the
expression of hippocampal brain-derived
neurotrophic factor transcripts following
voluntary physical activity. Neuroscience.
2003; 119(3): 32-721.