Comparison of twelve weeks of the high-intensity interval training and moderate-intensity continuous training on inflammatory biomarkers of cardiovascular disease predictor in obese menopause women

Document Type : original article

Authors

1 Department of Sports Physiology, Mahabad Branch, Islamic Azad University, Mahabad, Iran

2 Department of Exercise Physiology, Payam Noor, Tehran, Iran

Abstract

Purpose: Different studies have been shown that menopausal transition is associated with increased adiposity and inflammation, which leads to increase risk of CVD. However, Exercise training has been recomended as an effective approach to prevent and reduce these factors. Therefore, the aim of this study was to investigate and compare the effect of high-intensity interval training and moderate-intensity continuous training on inflammatory biomarkers of cardiovascular disease predictor in obese menopause women.
Methods: 40 menopause obese women in a semi-experimental with pre-test and post-test design, randomly assigned into three groups of control, high intensity interval (6-12×60s of high intensity training (85–95% HRR)) and moderate-intensity continuous (25-30 min aerobic exercise at 40%–65% heart rate reserve(HRR)). Exercise training programs for the two experimental groups were performed three sessions per week for 12 weeks. Data were analyzed by paired t-test and one-way analysis of variance tests at the significance level of 0.05.
Results: The results indicated that both type of exercise training have a significant effect on the CRP (tHIIT=7.278, p=0/000; tMICT=5/059, P = 0/000) and ICAM-1 (tHIIT=7.813, P = 0/000; tMICT=4/609, P = 0/000) concertation. Hovewer, these biomarkers unchanged in the control group (P > 0.05). Moreover, compared to moderate-intensity continuous training, high-intensity interval training demonstrated greater reduction in CRP (percent of change: 22.91% vs 44.02% P = 0.000) and ICAM-1 (percent of change: 21.17% vs 30.74% p=0.041). The results also indicated that the changes in CRP and ICAM-1 concentrations correlated (R) with the changes in body composition indices after training (P < 0.05).
Conclusion: In conclusion, the results of this study showed that despite of the effectiveness of both training program, high intensity training has predominant effect on inflammatory biomarkers of cardiovascular disease predictor in obese menopause women.

Keywords

References

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History

  • Receive Date: 04 March 2020
  • Revise Date: 11 April 2021
  • Accept Date: 21 April 2021
  • First Publish Date: 23 September 2021
  • Publish Date: 23 September 2021

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