Effect of 8 weeks of aerobic interval training on levels of lipocalin-2, glucose, insulin and insulin resistance in Obesity women

Document Type : original article

Abstract



Introduction: Obesity is associated with many cardiovascular and metabolic diseases including insulin resistance.
NGAL, as an adipockin secreted from fat tissues, has been recently indicated to be particularly related to obesity
and insulin resistance. The purpose of this study was to examine the effect of an interval period of aerobic training
on plasma levels of lipocalin-2, insulin ,glucose and Homeostatic model assessment ( (HOMA-IR) in obese women.
Methodology: 18 sedentary obese women (BMI30 Kg/m2) were randomly assigned into experimental and
control groups and were asked to participate in interval aerobic training sessions with moderate intensity (60-75%
of Reserve Heart Rate)(HRR) for 8 weeks(three days a week,60 min per session). Plasma levels of lipocalin2,
insulin, glucose and (HOMA-IR) Two blood samples were taken ( after 12 hours fasting ) before and 48 hours after
final trianing session. Data were analyzed by using (ANCOVA), paired dependent t-test and Pearson correlation at
the (P <0.05). Results: The result while 8 weeks of interval aerobic training with moderate intensity showed a
significant change in insulin (P <0.05) and HOMA-IR (P <0.05), changes in plasma levels NGAL (P>0.05) and
glucose (P>0.05) tuned out insignificant. Moreover, there was no significant relationship between the level of
lipocalin 2 and values of glucose, insulin and HOMA-IR (P>0.05). Conclusion: the results of this study indicated
that this kind of training improved insulin resistance; however, a definite statement about the changes in NGAL
levels warrants further research.

Keywords

References

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Journal of Sport and Exercise Physiology
Volume 8, Issue 1 - Serial Number 15
February 2016
Pages 1157-1166

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History

  • Receive Date: 09 February 2016
  • Revise Date: 11 June 2024
  • Accept Date: 31 December 2020
  • First Publish Date: 31 December 2020
  • Publish Date: 21 April 2015

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