The difference of myostatin gene expression in fast and slow twitch healthy male rat after eight weeks of high intensity interval training

Document Type : original article

Abstract

The difference of myostatin gene expression in fast and slow twitch healthy male rat after eight weeks of high intensity interval training
The aim of the present study was to assess differences in myostatin gene expression in slow and fast-twitch
muscles of healthy male rats after 8 weeks high intensity interval training. Methods: For this purpose, 12 male
Wistar rats divided into two groups, control (6 = n) and trained (6 = n). High intensity interval training was
five days a week for eight weeks. Each session was formed from three intervals (four-minute with intensity of
90 to 100% VO2max and two- minute with intensity of 50 to 60% VO2max). 24 hours after the last training
session, the Extensor digitorum longus and soleus muscle were extracted and gene expression levels were
measured by RT-PCR. Result: Statistical analysis using independent t-test showed that the soleus and EDL
muscles myostatin levels decreased significantly in the experimental group compared with the control group
(0/001 = p). Conclusion: Hence it can be concluded that myostatin expression in both EDL and soleus muscle
is reduced by high intensity interval training.

Keywords

References

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Journal of Sport and Exercise Physiology
Volume 9, Issue 1 - Serial Number 17
March 2017
Pages 1301-1306

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History

  • Receive Date: 13 September 2016
  • Revise Date: 11 June 2024
  • Accept Date: 31 December 2020
  • First Publish Date: 31 December 2020
  • Publish Date: 21 May 2016

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