Journal of Sport and Exercise Physiology

Journal of Sport and Exercise Physiology

Metabolic responses following aquatic vs. land exercise in trained diabetic postmenopausal women: the role of ANP and Epinephrine

Document Type : original article

Authors
Sima Nasiri
Azam Zarshanshan
Karim Azali Alamdari
Department of Sports Science, Faculty of Educational Sciences and Psychology, Shahid Madani University of Azerbaijan, Tabriz, Iran
10.52547/joeppa.15.1.107
Abstract
Purpose: The metabolic benefits from each individual exercise session (in land vs. water condition) designated for trained diabetic patients remain to be evaluated. The aim of this study was to invesigate blood glucose, FFA, insulin, ANP and epinepherin levels during land vs. water cycling session and also following early post exercise recovery period.
Methods: This was a case-crossover study with time series method. Twelve postmenopausal diabetic women (age 66.76 ± 2.3 years), participated in three distinct test sessions with glucose tolerance test at the begining, at control, water and land exercise conditions, following participating in an interval training protocol (six weeks). Both aquatic and land exercise sessions were consisted of three sets of ten min cycling intervals at 40% of Vo2max. Blood sampling were done in five occasions each session including: pre exercise, immediately post exercise and also at 60th, 90th and 120 th min of post exercise period. The data were analyzed by factorial (3×5; three five phase series) ANOVA for repeated measurements using SPSS 21.
Results: acute cycling in both water and land conditions decreased blood glucose (-37% and -39%), insulin (-20% and -17%) and FFAs (-61% and -55%), while serum ANP (169% and 52%) and epinephrine (43% and 82%) were up regulated (P < 0.05). Serum Insulin, FFAs and ANP levels were elevated also followingthe exercise cessation, with a synergic suppression of blood glucose and epinephrine levels (P < 0.05). All measured variables levesl were lower in water exercise session compared to land exercise (P < 0.05).
Conclusions: more beneficial metabolic effects could be provided with an individual training session performed by regularly exercising diabetic patients in water condioton, compared to land exercise and this trend was continued through two hours of recovery period. However; more investigations remain to be done because of the lack of similar evidence and study limitations.
Keywords
Exercise Prescription
Metabolism
Diabetes Mellitus
  1. Kemps, H., et al., Exercise training for patients with type 2 diabetes and cardiovascular disease: what to pursue and how to do it. A position paper of the European Association of Preventive Cardiology (EAPC). 2019. 26(7): p. 709-727.
  2. American Diabetes, A., Standards of Medical Care in Diabetes-2019 Abridged for Primary Care Providers. Clinical diabetes : a publication of the American Diabetes Association, 2019. 37(1): p. 11-34.
  3. Bird, S.R. and J.A. Hawley, Update on the effects of physical activity on insulin sensitivity in humans. BMJ open sport & exercise medicine, 2017. 2(1): p. e000143-e000143.
  4. Heras-Molina, A., et al., Short-Term Effects of Early Menopause on Adiposity, Fatty Acids Profile and Insulin Sensitivity of a Swine Model of Female Obesity. Biology, 2020. 9(9): p. 284.
  5. Slopien, R., et al., Menopause and diabetes: EMAS clinical guide. Maturitas, 2018. 117: p. 6-10.
  6. Mumusoglu, S. and B.O. Yildiz, Metabolic Syndrome During Menopause. Current Vascular Pharmacology, 2019. 17(6): p. 595-603.
  7. Kurobe, K., et al., Metabolic responses to exercise on land and in water following glucose ingestion. Clinical physiology and functional imaging, 2018. 38(2): p. 227-232.
  8. Irandoust, K. and M. Taheri, The effects of aquatic exercise on body composition and nonspecific low back pain in elderly males. Journal of physical therapy science, 2015. 27(2): p. 433-435.
  9. Carter, H., et al., Oxygen Uptake Kinetics in Treadmill Running and Cycle Ergometry: A Comparison. Cardiopulmonary Physical Therapy Journal, 2001. 12(1): p. 22.
  10. Masumoto, K., D. Delion, and J. Mercer, Insight into muscle activity during deep water running. Medicine and science in sports and exercise, 2009. 41(10): p. 1958.
  11. Fujishima, K., et al., Thermoregulatory responses to low-intensity prolonged swimming in water at various temperatures and treadmill walking on land. Journal of physiological anthropology and applied human science, 2001. 20(3): p. 199.
  12. Hargreaves, M., et al., Effect of heat stress on glucose kinetics during exercise. Journal of applied physiology (Bethesda, Md.: 1985), 1996. 81(4): p. 1594.
  13. Fenzl, M., et al., Release of ANP and fat oxidation in overweight persons during aerobic exercise in water. International journal of sports medicine, 2013. 34(09): p. 795-799.
  14. Wiesner, S., et al., Neurohumoral and metabolic response to exercise in water. Hormone and metabolic research, 2010. 42(05): p. 334-339.
  15. Stich, V., et al., Adipose tissue lipolysis is increased during a repeated bout of aerobic exercise. Journal of Applied Physiology, 2000. 88(4): p. 1277-1283.
  16. Williams, J.E., et al., Exercise Considerations For Type 1 And Type 2 Diabetes. Acsm's Health & Fitness Journal, 2018. 22(1): p. 10-16.
  17. Cunha, R.M., et al., Acute blood pressure response in hypertensive elderly women immediately after water aerobics exercise: A crossover study. Clinical and Experimental Hypertension, 2017. 39(1): p. 17-22.
  18. Matomäki, P., H. Kainulainen, and H. Kyröläinen, Corrected whole blood biomarkers–the equation of Dill and Costill revisited. Physiological Reports, 2018. 6(12): p. e13749.
  19. Azali Alamdari, K. and H. Rohani, Effects of normobaric and hypobaric endurance training on metabolic risk factors in midlife men. Iranian Journal of Endocrinology and Metabolism, 2015. 17(2): p. 113-123.
  20. Bae, J.H., et al., Postprandial glucose-lowering effect of premeal consumption of protein-enriched, dietary fiber-fortified bar in individuals with type 2 diabetes mellitus or normal glucose tolerance. Journal of Diabetes Investigation, 2018. 9(5): p. 1110-1118.
  21. Willemsen, J., et al., Highly sensitive and specific HPLC with fluorometric detection for determination of plasma epinephrine and norepinephrine applied to kinetic studies in humans. Clinical chemistry, 1995. 41(10): p. 1455-1460.
  22. Ichiki, T. and J.C. Burnett Jr, Atrial Natriuretic Peptide―Old But New Therapeutic in Cardiovascular Diseases―. Circulation Journal, 2017. 81(7): p. 913-919.
  23. Kemmler, W., et al., Acute hormonal responses of a high impact physical exercise session in early postmenopausal women. European Journal of Applied Physiology, 2003. 90(1): p. 199-209.
  24. Belo, N.O., M.R. Sairam, and A.M. Dos Reis, Impairment of the natriuretic peptide system in follitropin receptor knockout mice and reversal by estradiol: implications for obesity-associated hypertension in menopause. Endocrinology, 2008. 149(3): p. 1399-406.
  25. Hamada, M., et al., Plasma levels of atrial and brain natriuretic peptides in apparently healthy subjects: Effects of sex, age, and hemoglobin concentration. International Journal of Cardiology, 2017. 228: p. 599-604.
  26. Alis, R., et al., Hemoconcentration induced by exercise: Revisiting the D ill and C ostill equation. 2015. 25(6): p. e630-e637.
  27. Wilcock, I.M., J.B. Cronin, and W.A.J.S.m. Hing, Physiological response to water immersion. 2006. 36(9): p. 747-765.
  28. Nakagawa, Y., T. Nishikimi, and K. Kuwahara, Atrial and brain natriuretic peptides: Hormones secreted from the heart. Peptides, 2019. 111: p. 18-25.
  29. Terblanche, E. and A.M.J.E.j.o.a.p. Millen, The magnitude and duration of post-exercise hypotension after land and water exercises. 2012. 112(12): p. 4111-4118.
  30. Mora-Rodriguez, R. and E.F. Coyle, Effects of plasma epinephrine on fat metabolism during exercise: interactions with exercise intensity. American Journal of Physiology-Endocrinology And Metabolism, 2000. 278(4): p. E669-E676.
  31. Tauscher, S., et al., Role of atrial natriuretic peptide (ANP) in the regulation of insulin secretion and vitality of pancreatic ß cells. BMC Pharmacology & Toxicology, 2015. 16(Suppl 1): p. A92-A92.
  32. Ratge, D., et al., Free and conjugated catecholamines in human plasma during physical exercise. 1986. 13(7): p. 543-553.
  33. Ma, Y., et al., Recurrent hypoglycemia inhibits the counterregulatory response by suppressing adrenal activity. The Journal of clinical investigation, 2018. 128(9): p. 3866-3871.
  34. Isacco, L., P. Duché, and N. Boisseau, Influence of Hormonal Status on Substrate Utilization at Rest and during Exercise in the Female Population. Sports Medicine, 2012. 42(4): p. 327-342.
  35. Röhling, M., et al., Influence of acute and chronic exercise on glucose uptake. Journal of diabetes research, 2016. 2016.
  36. Consitt, L.A., J.A. Bell, and J.A.J.I.l. Houmard, Intramuscular lipid metabolism, insulin action, and obesity. 2009. 61(1): p. 47-55.
  37. Horowitz, J.F.J.E. and s.s. reviews, Regulation of lipid mobilization and oxidation during exercise in obesity. 2001. 29(1): p. 42-46.
  38. Lundsgaard, A.-M., A.M. Fritzen, and B. Kiens, Molecular regulation of fatty acid oxidation in skeletal muscle during aerobic exercise. Trends in Endocrinology & Metabolism, 2018. 29(1): p. 18-30.
  39. Kanaley, J.A., et al., Fatty acid kinetic responses to running above or below lactate threshold. Journal of applied physiology, 1995. 79(2): p. 439-447.
  40. Verboven, K., et al., Adrenergically and non-adrenergically mediated human adipose tissue lipolysis during acute exercise and exercise training. Clin Sci (Lond), 2018. 132(15): p. 1685-1698.
  41. Thyfault, J.P. and A. Bergouignan, Exercise and metabolic health: beyond skeletal muscle. Diabetologia, 2020: p. 1-11.

  • Receive Date 17 August 2020
  • Revise Date 31 October 2020
  • Accept Date 23 November 2020
  • First Publish Date 21 March 2022
  • Publish Date 21 March 2022