تاثیر دو نوع برنامه تمرین مقاومتی بر سطوح BDNF بزاقِ کودکان

نوع مقاله : علمی - پژوهشی

نویسندگان

1 دانشجوی کارشناسی ارشد تربیت بدنی و علوم ورزشی دانشگاه شهید بهشتی

2 عضو هیئت علمی دانشکده تربیت بدنی و علوم ورزشی دانشگاه شهید بهشتی

3 کارشناس ارشد فیزیولوژی ورزشی دانشگاه شهید بهشتی

چکیده

هدف: با توجه به پتانسیل بالای شکل‎پذیری عصبی در کودکان، یافتن بهترین روش‎های تمرینی برای رسیدن به سازگاری های عصبی مناسب  بسیار حائز اهمیت است. BDNFبه عنوان عضوی از خانواده نروتروفین ها، یکی از شاخص های رشد عصبی است که در پاسخ به فعالیت ورزشی افزایش می یابد .هدف اصلی این تحقیق بررسی اثر دو نوع تمرین مقاومتی ثابت و معلق بر سطوح BDNFبزاق کودکان نابالغ است.روش شناسی: 24 نفر از پسران نابالغ (میانگین سنی 55/0 3/12، مرحله 1 و2 از مقیاس تانر) در سه گروهِ تمرین مقاومتی معلق (TRX)، تمرین مقاومتی با وزن بدن (BWT)،و گروه کنترل(C) تقسیم شدند. گروه‌های تمرین، دو جلسه در هفته و به مدت هشت هفته به تمرین پرداختند. همه گروه‎ها سه روز در هفته در تمرینات منظم فوتبال شرکت می کردند. نمونه بزاق، قبل از شروع تمرینات و 72 ساعت پس از آخرین جلسه تمرین جمع‌آوری و میزان BDNFبزاق با روش الایزا سنجیده شد. از آزمونِ آنوای یک طرفه با سطح معنی داری 55/0 برای مقایسه بین گروه‌ها استفاده شد.نتایج: با وجود اینکه اثر تمرین مقاومتی بر قدرت عضلات پایین تنه در گروه تجربی به خوبی مشاهده شد، غلظت BDNFبزاق تفاوت معنی داری در بین گروه‎ها نداشت (411/0=P ، 922/0=F ).بحث و نتیجه گیری: از آن‎جا که کودکان تحت تاثیر فرآیندهای رشد و بلوغ قرار دارند، به تغییرات ناشی از فعالیت ورزشی در نروتروفین‎ها، حساسیت بیشتری دارند در نتیجه یافته‎های مشابه می‎تواند به دلیل شرکت منظم همه گروه‎ها در تمرینات فوتبال باشد.

عنوان مقاله [English]

The effect of two types of resistance training on salivary BDNF of preadolescence children

نویسندگان [English]

  • Aynaz Pourmotahari 1
  • Rana Fayazmilani 2
  • Ahad Abbasi 3
1 Master Student of Exercise Physiology, Shahid Beheshti University
2 Faculty member of Shahid Beheshti University, Exercise Physiology
3 MS in Exercise Physiology, Shahid Beheshti University
چکیده [English]

Purpose: According to high potential of neural plasticity in childhood, it is important to find the best training methods to reach proper neural adaptation. BDNF is a member of the neurotrophins which is engaged in neuromuscular adaptations due to increased muscular activity. The main purpose of this study is to investigate the effects of two types of suspension and unsuspension resistance training on salivary BDNF of prepubescent children.
Method: 24 immature boys (mean age 12.3±0.55, Tanner stage of 1 and 2) were divided into three groups of TRX suspension training (TRX), body weight training (BWT), and control (C). Training groups completed training programs, two times a week for eight weeks. Saliva samples were collected before training and also 72 hours after last training session to measure salivary BDNF using ELIZA method. One-way ANOVA test with significance level of 0.05 was used for comparison between groups.
Results: Even though the effects of resistance training on muscle strength in the lower body was observed in the experimental group, BDNF concentrations were not significantly different (F=.922, P=.411).
Conclusion: Since children are affected by growth and maturation processes, they are more susceptible to exercise-induced changes in neurotrophins, similar results between groups, may be due to regular participation in soccer training in all three groups.

کلیدواژه‌ها [English]

  • Suspension Training-Children trainability- Neurotrophic Factor
Cardon G VCE, de Bourdeaudhuij I. Physical activity in infants and toddlers., 2011:1-6 Eoecd.1-6.
Strong WB MR, Blimkie CJ, Daniels SR, Dishman RK, Gutin B, et al. Evidence based, 2005;146(6):732-7 pafs-ayTJop.
Barbieri DaLZ, . Strength training for children and adolescents: Benefits and risks. Collegium antropologicum, . 2013. 37(2): p. 219-225.
Pediatrics. PAAAo. Committee on Sports Medicine and Committee on School Health: Organized athletics for preadolescent children. Pediatrics. 1989; 84(3):583-4
N. M. The growing child in sport. British medical bulletin. 1992;48(3):561-8.
Hass CJ, M.S. Feigenbaum, and B.A. Franklin, . Prescription of resistance training for healthy populations. Sports medicine, 2001. 31(14): p. 953-964.
Blimkie CJ. Resistance training during preadolescence. Sports Medicine, 1993. 15(6): p. 389-407.
adres E, et al.,. The effect of long-term resistance training on anthropometric measures, muscle strength, and self concept in pre-pubertal boys. Pediatric Exercise Science, 2001. 13(4): p. 357-372.
Falk BaAE. Resistance training, skeletal muscle and growth. Pediatric endocrinology reviews: PER, 2003. 1(2): p. 120-127.
McNeely EaLA. Strength training for children: a review and recommendations. Physical and Health Education Journal, 2002. 68(4): p. 4-9.
Behm DG, et al., Canadian Society for Exercise Physiology position paper: . resistance training in children and adolescents. Applied Physiology, Nutrition, and Metabolism, 2008. 33(3): p. 547-561.
Faigenbaum AD, et al., . Youth resistance training: updated position statement paper from the national strength and conditioning association. The Journal of Strength & Conditioning Research, 2009. 23: p. S60-S79.
McCambridge TaPS. Strength training by children and adolescents. Pediatrics, 2008. 121(4): p. 835-840.
Snarr RLaMRE. Comparison of Electromyographic Activity When Performing an Inverted Row With and Without a Suspension Device. Age (yrs), 2013. 26(4.2): p. 22.3-1.0.
Byrne JM, et al., . The Effect of Using a Suspension Training System on Muscle Activation During the Performance of a Front Plank Exercise. Journal of strength and conditioning research/National Strength & Conditioning Association, 2014.
T. Heltne ea. Effects of TRX versus Traditional Training Programs on Core Endurance and Muscular Strength 2013.
Ronald L. Snarr ea. Electromyographic Activity of Rectus Abdominis during a Suspension Push-Up Compared to Traditional Exercises. 2013.
Klein R NV, Jing SA, Lamballe F, Tapley P, Bryant S, et al. . The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3. Cell 1991; 66: 395–403.
Ibanez CF ET, Persson H. . Chimeric molecules with multiple neurotrophic activities reveal structural elements determining the specificities of NGF and BDNF. EMBO J 1991; 10: 2105–2110.
Cohen_Croy S LB. Neurotrophic regulation of retinal ganglion cell synaptic connectivity :from axons and dendrites synapses .2004.
Egan MF, Kojima, M., Calicott, J.H., Goldberg, T.E., Kolachana, B.S., Bertolino, A. Zaitsev, E., Gold, B., Goldman, D. Dean, M. Lu, B. Weinberger, D.R. . “BDNF val66 net polymorphism affects activity – dependent secretion of BDNF and human memory and hippocampal function”. Cell, 2003;112(2):257-69.
Hennigan A OCR, Kelly AM. Neurotrophins and their receptors: roles in plasticity, neurodegeneration and neuroprotection. Biochem Soc Trans 2007; 35: 424-7.
MV. J. Plasticity in the developing brain: implications for rehabilitation. Dev Disabil Res Rev 2009; 15: 94-101.
Neeper SA Gm-PF, Choi J, et al. . Exercise and brain neurotrophins [letter]. Nature 1995; 373 (6510): 109.
Vaynman S G-PF. License to run: exercise impacts functional plasticity in the intact and injured central nervous system by using neurotrophin. Neurorehab Neur Repair 2005; 19 (4): 283-94.
Kristel Knaepen MG, 1,2 Elsa Marie Heyman1,3 and Romain Meeusen1. Neuroplasticity – Exercise-Induced Response of Peripheral Brain-Derived Neurotrophic Factor 2010;40(9):765-801
Yarrow JF WL, McCoy SC, et al. . Training augments resistance exercise induced elevation of circulating brain derived neurotrophic factor (BDNF). Neurosci Lett 2010; 479 (2): 161-5
Goekint M DPK, Roelands B, et al. . Strength training does not influence serum brain-derived neurotrophic factor. Eur J Appl Physiol. 2010;110(2):285-93.
Poduslo JF CG. Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF. Brain Res Mol Brain Re1996; 36: 280-6.
Pan W BW, Fasold MB, et al. . Transport of brainderived neurotrophic factor across the blood-brain barrier. Neuropharmacol 1998; 37: 1553-61.
Seifert T BP, Wissenberg M, et al. Endurance training enhances BDNF release from the human brain. Am J Physiol Regul Integr Comp Physiol 2010; 298 (2): R372-7.
Matthews VB AmM, Chan MH, et al. Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase. Diabetologica 2009; 52 (7): 1409-18.
Nakahashi T FH, Altar CA. . Vascular endothelial cells synthesize and secrete brain-derived neurotrophic factor. FEBS Lett 2000; 470: 113-7.
Tsukinoki K SJ, Sasaguri Y, et al. . Immobilization stress induces BDNF in rat submanidbular glands. J Dent Res 2006; 85: 844-8
Tsukinoki K SJ, Muto N, et al. Submandibular glands contribute to increase in plasma BDNF. J Dent Res 2007; 86: 260-4.
Schiffer T SS, Hollmann W, et al. Effects of strength and endurance training on brain-derived neurotrophic factor and insulin-like growth factor 1 in humans. Horm Metab Res 2009; 41 (3): 250-4.
E.V. Pitts SP, D.M. Hess, R.J. Balice-Gordon, . Neurotrophin and Trkmediated signaling in the neuromuscular system, International Anesthesiology Clinics 44 (2006) 21–76.
Begliuomini S. LE, Ninni F., Casarosa E., Merlini S., Pluchino N.,, Valentino V. LM, Luisi M. and Genazzani A.R. . Plasma brain-derived neurotrophic factor daily variations in men: correlation with cortisol circadian rhythm. J. Endocrinol.2008. 197, 429-435.
Pinnock S.B. BR, Chan M., Hunt L.T., Turner-Stokes T. and, J. H. Interactions between nitric oxide and corticosterone in the regulation of progenitor cell proliferation in the dentate gyrus of the adult rat. Neuropsychopharmacology .(2007).32, 493-504.
Tsukinoki K. SJ, Sasaguri K., Miyoshi Y., Jinbu Y., Kusama M. SSaWY. Immobilization stress induces BDNF in rat submandibular glands. J. Dent. Res. 2006; 85: 844-8
Saruta J. LT, Shirasu M., Takahashi T., Sato C., Sato S. and, K. T. Chronic stress affects the expression of BDNF in rat submandibular glands. Stress)2010). 13, 53-60.
Chan KL TK, Yip SP. . Relationship of serum brainderived neurotrophic factor (BDNF) and health-related lifestyle in healthy human subjects. Neurosci Lett 2008; 447 (2-3): 124-12.
Nofuji Y SM, Moriyama Y, et al. . Decreased serum brain-derived neurotrophic factor in trained men. Neurosci Lett 2008; 437 (1): 29-32.
Seifert T BP, Wissenberg M, et al. . Endurance training enhances BDNF release from the human brain. Am J Physiol Regul Integr Comp Physiol 2010; 298 (2): R372-7.
Monteleone P TA, Martiadis V. . Opposite changes in the serum brain-derived neurotrophic factor in anorexia nervosa and obesity. Psychosom Med 2004; 66: 744-8.
Lommatzsch M ZD, Schuhbaeck K. The impact of age, weight and gender on BDNF levels in human platelets and plasma. Neurobiol Aging 2005; 26: 115-23.
Currie J RR, Ludlow H, et al. . Cardio-respiratory fitness, habitual physical activity and serum brain derived neurotrophic factor (BDNF) in men and women. Neurosci Lett 2009; 451 (2): 152-5.
E. W. Athletes’ anaemia: a review of possible causes and guidelines on investigation. Br J Sports Med 1989; 23: 81-3.
Schulz K GS, Witte J, et al. Impact of aerobic training on immune-endocrine parameters, neurotrophic factors, quality of life and coordinative function in multiple sclerosis. J Neurol Sci 2004; 225 (1-2): 11-8.
Castellano V WL. Serum brain-derived neurotrophic factor response to aerobic exercise in multiple sclerosis. J Neurol Sci 2008; 269 (1-2): 85-91.
Baker LD FL, Foster-Schubert K, et al. . Effects of aerobic exercise on mild cognitive impairment. Arch Neurol 2010; 67(1): 71-9
Katoh-Semba R WR, Komori T. . Age-related changes in BDNF protein levels in human serum: differences between autism cases and normal controls. Int J Devl Neurosci 2007; 25: 367-72.
Vaynman S G-PF. Revenge of the “sit”: how lifestyle impacts neuronal and cognitive health through molecular systems that interface energy metabolism with neuronal plasticity. J Neurosci Res 2006.84:699–715.