Journal of Sport and Exercise Physiology

Journal of Sport and Exercise Physiology

Comparison of twelve weeks of the high-intensity interval training and moderate-intensity continuous training on inflammatory biomarkers of cardiovascular disease predictor in obese menopause women

Document Type : original article

Authors
Sirvan Atashk 1
Vahideh Kianmarz Bonab 2
Reza Roshdi Bonab 1
1 Department of Sports Physiology, Mahabad Branch, Islamic Azad University, Mahabad, Iran
2 Department of Exercise Physiology, Payam Noor, Tehran, Iran
10.52547/joeppa.14.2.101
Abstract
Purpose: Different studies have been shown that menopausal transition is associated with increased adiposity and inflammation, which leads to increase risk of CVD. However, Exercise training has been recomended as an effective approach to prevent and reduce these factors. Therefore, the aim of this study was to investigate and compare the effect of high-intensity interval training and moderate-intensity continuous training on inflammatory biomarkers of cardiovascular disease predictor in obese menopause women.
Methods: 40 menopause obese women in a semi-experimental with pre-test and post-test design, randomly assigned into three groups of control, high intensity interval (6-12×60s of high intensity training (85–95% HRR)) and moderate-intensity continuous (25-30 min aerobic exercise at 40%–65% heart rate reserve(HRR)). Exercise training programs for the two experimental groups were performed three sessions per week for 12 weeks. Data were analyzed by paired t-test and one-way analysis of variance tests at the significance level of 0.05.
Results: The results indicated that both type of exercise training have a significant effect on the CRP (tHIIT=7.278, p=0/000; tMICT=5/059, P = 0/000) and ICAM-1 (tHIIT=7.813, P = 0/000; tMICT=4/609, P = 0/000) concertation. Hovewer, these biomarkers unchanged in the control group (P > 0.05). Moreover, compared to moderate-intensity continuous training, high-intensity interval training demonstrated greater reduction in CRP (percent of change: 22.91% vs 44.02% P = 0.000) and ICAM-1 (percent of change: 21.17% vs 30.74% p=0.041). The results also indicated that the changes in CRP and ICAM-1 concentrations correlated (R) with the changes in body composition indices after training (P < 0.05).
Conclusion: In conclusion, the results of this study showed that despite of the effectiveness of both training program, high intensity training has predominant effect on inflammatory biomarkers of cardiovascular disease predictor in obese menopause women.
Keywords
C-reactive protein
Intra-cellular adhesive molecules
Menopause women
HIIT training
Continuous training
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Journal of Sport and Exercise Physiology
Volume 14, Issue 2 - Serial Number 28
September 2022
Pages 101-114

  • Receive Date 04 March 2020
  • Revise Date 11 April 2021
  • Accept Date 21 April 2021
  • First Publish Date 23 September 2021
  • Publish Date 23 September 2021