Document Type : original article


Department of Exercise Physiology , Faculty of Physical Education and Sport Sciences , University of Tehran, Tehran , Iran


Background and Purpose: The aim of this study was to investigate the effect of combined exercise on resting levels of pentraxin3 (PTX3) and serum amyloid A (SAA) in the plasma of men with type-2 diabetes.
Materials and Methods: Twenty oen-athlete men with type-2 diabetes were randomly divided into control and training groups. Combined training was performed for six weeks. Training including 25-35 minutes of aerobic exercise with an intensity of 55-75% of maximum heart rate and five resistance movements involving large muscles in the upper and lower body Includes five movements: chest press, army press, squat, dead lift, dumbbell rowing with an intensity of 55-75% of a maximum repetition with a frequency of three times a week with the periorizing of resistance training on aerobic training . The intensity of aerobic exercise was measured with heart rate monitor and the intensity of resistance training was measured every two weeks with a maximum repetition test. For data analysis, dependent and independent t-test was used at the significant level of P ≤ 0.05.
Results: Examining the results of the study, it was found that the training contract reduced the SAA index (16.7%) and significantly changed it in the training group compared to the control group (P = 0.047 . However, there was no effect on resting SAA in the control group and a 2.2% increase in PTX3 in the training group was not significant (P = 0.474).
Conclusion: According to the results of the study and a significant decrease in inflammatory factor SAA and increase in PTX3, it can be concluded that six weeks of combined training affects the levels of these factors in men with type-2 diabetes and can probably reduce inflammation in these patients.


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