Creatine and Glutamine are supplements that involve in protein metabolism. The present study examined the effects
of creatine and creatine-glutamine supplementation on the physiological and anthropometric characteristics of the
elite wrestlers. For this reason, 36 wrestlers volunteered in Mazandaran province. They were divided in three
homogeneous groups including creatine group as the experiment group 1 (n=12), creatine-glutamine group as the
experiment group 2 (n=12) and placebo group as the control group (n=12). In a pretest-posttest design,
anthropometric characteristics (weight, body fat percentage, BMI) and physiological characteristics (maximal
strength, peak power, average power, total work performed) were measured. For data analysis, Kolmogorov-
Smirnov test, Repeated Measure and one-way ANOVA were used (p<0.05) to measure examine the distribution of
normalized samples and compare the mean difference between groups respectively used. The Results showed that
there were not significant differences in weight, BMI, body fat percentage, peak power, average power and total
work performed between both experiment groups and control group. But There was a significant difference in
maximal strength between both experimental groups and control group (p=0.040) but it was not significant
difference between the experiment groups (p=0.60). It was concluded that creatine supplement and creatineglutamine
supplement influences maximal strength and it is suggested to be used by the athletes.