Consumption of anti-oxidant supplement decrease oxidative stress due to intensive exercise. The aim of this study was to investigate the effect of acute supplementary consumption of coenzyme Q10 on serum aspartate aminotransferase (AST) and Delayed Onset Muscle Soreness (DOMS) after a session of resistance exercise in male college athletes. eighteen male college athletes (age: 21.1±1.2 yr, weight: 72.5 ± 8.1 kg, height: 177.4 ± 7.3 cm, body mass index: 23.2 ± 2.1 kg/m2) with at least 6 months of regular exercise training, divided into Q10 supplement and placebo groups randomly. 120 minutes before exercise, subjects received either of the following regimens: Coenzyme Q10 (200 mg per subject) or placebo (Flour). All subjects underwent a circuit resistance exercise include 5 stations that performed in 3 sets with 75% of 1RM. AST concentration was measured before supplementation and immediately, 24, 48 hours after the exercise. DOMS, in addition of these times, were assessed within 72 hours after exercise. Data were analyzed by ANOVA with repeated measure, Bonferroni and independent t test at P≤0.05. The results shown that change in AST was not significantly different between two groups (Р=0.072). But changes in DOMS between the two groups was significant (Р=0.032). Based on the results, it seems that acute Q10 supplements can reduce DOMS (fatigue index) and serum AST (index of cellular damage) in male college athletes after resistance exercise.
Piercy, R.J., Hinchcliff, K.W., DiSilvestro, R.A., Reinhart, G.A., Baskin, C.R., Hayek, M.G., Burr, J.R., Swenson, R.A. (2000). Effect of dietary supplements containing antioxidants on attenuation of muscle damage in exercising sled doges, American journal of Veterinary research, 61 (11), 1438-1445.
Vassilakopoulos, T., Karatza, MH., Katsaounou, P., Kollinttza, A., Zakynthinos, S., Roussos, C. (2003). Antioxidnts attenuate the plasma cytocine response to exercise in humans. J Appl Physiol, 94: 1025-32.
Cooke, M., Iosia, M., Buford, T., Shelmadine, B., Hudson, G., Kerksick, C., et al. (2008). Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. J Int Soc Sports Nutr, 5:8.
Cordero, M.D., Cano-Garcia, F.J., Alcocer-Gomez, E., De Miguel, M., Sanchez-Alcazar, J.A. (2012). Oxidative stress correlates with headache symptoms in fibromyalgia: coenzyme Q10 effect on clinical improvement. 7:e35677.
Belardinelli, R., Muçaj, A., Lacalaprice, F., Solenghi, M., Seddaiu, G., Principi, F., et al. (2006). Coenzyme Q10 and exercise training in chronic heart failure. Eur Heart J, 27(22): 2675-81.
Zheng A, Moritani T (2008). Influence of CoQ10 on autonomic nervous activity and energy metabolism during exercise in healthy subjects. J Nutr Sci Vitaminol (Tokyo), 54(4): 286-90.
Lee, B.J., Lin, Y.C., Huang, Y.C., Ko, Y.W., Hsia, S., Lin, P.T. (2012). The relationship between coenzyme Q10, oxidative stress, and antioxidant enzymes activities and coronary artery disease, The Scientific Word Journal, Article ID 792756, 8.
Kanter, M.M., Lesmes, G.R., karmisky, L.A., La Ham-Saeger, J., Nequin, N.D. (1998). Serum creatine kinase and lactate dehydrogenase changes following an eighty kilometer race. Relationship to lipid peroxidation, Eur J Appl Physiol Occup Physiol., 57(1): 60-3.
Nevin, A.G., Hazar, S., Erbas, D. (2007). Effect of different resistance exercise protocols on nitric oxide, lipid peroxidation and creatine kinase activity in sedentary males, Journal of sport science andmedicine, 6(41): 417-422.
Deminice, R., Sicchieri, T., Mialich, M.S. Milani, F. Ovidio, P.P., Jordão, A.A. (2011). Oxidative stress biomarker responses to an acute session of hypertrophy-resistance traditional interval training and circuit training. International J Strength Cond Res, 25(3):798-804.
Deminice, R., Sicchieri, T., Mialich, M.S., Milani, F., Ovidio, P.P., Jordao, A.A. (2011). Oxidative stress biomarker responses to an acute session of hypertrophy-resistance traditional interval training and circuit training. J Strength Cond Res, 25(3): 798-804.
Kon, M., Kimura, F., Akimoto, T., Tanabe, K., Murase, Y., Ikemune, S. (2007). Effect of Coenzyme Q10 supplementation on exercise-induced muscular injury of rats. Exerc Immunol Rev, 13: 76-88.
Kon, M., Tanabe, K., Akimoto, T., Kimura, F., Tanimura, Y., Shimizu, K. (2008). Reducing exercise-induced muscular injury in kendo athletes with supplementation of coenzyme Q10. Br J Nutr, 100: 903-9.
He, L., Li, G., Feng, X., Shi, H., Chang, D., Ye, K. (2008). Effect of energy compound on skeletal muscle strain injury and regeneration in rats. Ind Health. 46: 506-12.
Kastello. GM., Consdorf, A., Hunter, A., Martin, H., Patterson, B., Sheehan, A., et al. (2008). The effects of Watkins antioxidant supplement on DOMS and serum oxidative damage biomarkers. Med Sci Sport Exerc, 40(5): 244-50.
فلاح محمدی ضیاء، دبیدی روشن ولی الله، کانعمتی حسین (1390)، اثر مصرف مکمل ویتامین E بر تغییرات نیتریک اکساید، LDH،و CPK پلاسمای مردان غیر فعال به دنبال یک جلسه تمرین مقاومتی. مجله المپیک، سال نوزدهم شماره 3.
مسافری ضیائ الدینی محمد، ابراهیم خسرو، امانی داور، عرب نرمی زهرا(1391)، تاثیر مصرف مکمل Q10 بر سطوح سرمیTNF-α طی فعالیت بدنی شدید. مجله دانشگاه علوم پزشکی اردبیل ، دوره 12 شماره3.
الهی افسانه، علیجانی عیدی، حجت شهلا(1390)، تاثیر آلیسین بر کوفتگی عضلانی تأخیری و بر برخی آنزیمهای پلاسمایی در ورزشکاران. مجله فیزیولوژی ورزشی، شماره 12.
Melzack, R. (1975) The McGill Pain Questionnaire: Major properties and scoring methods. Pain. 1: 277-299.
Stein, C., Mendl, G. (1988).The German counterpart to McGill Pain Questionnaire. Pain. 32: 251-255.
Grafton, K.V., Foster, N.E., Wright, C.C. (2005).Test retest reliability of the Short Form McGill Pain Questionnaire: assessment of intraclass correlation coefficients and limits of agreement in patients with osteoarthritis. Clin J Pain.21 (1): 73-82.
Liu, J.F., Chang, W.Y., Chan, K.H., Tsai, W.Y., Lin, C.L., Hsu, M.C. (2005). Blood lipid peroxides and muscle damage increased following intensive resistance training of female weightlifters, Ann.N.Y.Acad.Sci (1042): 255-261.
Cavas, L., Tarhan, L. (2004). Effect of vitamin-mineral supplementation on cardiac marker and radical scavenging enzymes, and MDA levels in young swimmers. 9TInt J Sport Nutr Exerc Metab9T, 14(2): 46-133.
Littarru, G.P., Tiano, L. (2007). Bioenergetic and antioxidant properties of coenzyme Q10: recent developments. Mol Biotechnol, 37: 31-7.
Zuliani, U., Bonetti, A., Campana, M., Cerioli, G., Solito, F., Novarini, A. (1989). The influence of ubiquinone (Co Q10) on the metabolic response to work. J Sports Med Phys Fitness, 29: 57-62.
Fu, X., Ji, R., Dam, J. (2010). Antifatigue effect of coenzyme Q10 in mice. J Med Food, 13: 211-5.
Greer, B.K. (2006). Dissertation: The effects of Branched-chain amino acid supplementation on indirect indicators of muscle damage and performance, ProQuest Information and Learning Company.
lenn, J., Uhi, T., Matacola, C., Boissonneault, G., Yates, J., Ibrahim, w. and Bruckner, G. (2005). The effects of fish oil and Isoflavones on Delayed Onset muscle soreness. Medicine & Science in sport & Exercise, 1889-1897.
McBride, J.M., Kraemer, W.J., McBride, T.T., Sebastianelli, W. (1998). Effect of resistance exercise on free radical production. Med Sci Sports Exer, 30: 67–72.
(2015). Effect of coenzyme Q10 consumption before one session of resistance exercise on serum AST and Delayed Onset Muscle Soreness in male college athletes. Journal of Sport and Exercise Physiology, 7(2), -. doi: 10.48308/joeppa.2015.98715
MLA
. "Effect of coenzyme Q10 consumption before one session of resistance exercise on serum AST and Delayed Onset Muscle Soreness in male college athletes". Journal of Sport and Exercise Physiology, 7, 2, 2015, -. doi: 10.48308/joeppa.2015.98715
HARVARD
(2015). 'Effect of coenzyme Q10 consumption before one session of resistance exercise on serum AST and Delayed Onset Muscle Soreness in male college athletes', Journal of Sport and Exercise Physiology, 7(2), pp. -. doi: 10.48308/joeppa.2015.98715
VANCOUVER
Effect of coenzyme Q10 consumption before one session of resistance exercise on serum AST and Delayed Onset Muscle Soreness in male college athletes. Journal of Sport and Exercise Physiology, 2015; 7(2): -. doi: 10.48308/joeppa.2015.98715