Comparison of the effects of 8 weeks of high intensity interval training and continuous training on P-selectin expression and platelet indices in cardiovascular disease

Document Type : original article

Abstract



Platelets play an important role in the etiology of cardiovascular disease. The aim of this study was to
compare the effects of 8 weeks of high intensity interval training and continuous training on P-selectin
expression and platelet indices in cardiovascular patients. Therefore, 30 CABG and PCI heart patient
voluntary participated and divided into three groups (n=10): control, continuous and high-intensity interval
group. Anthropometric characteristics and peak oxygen consumption was recorded before starting a workout.
Each session was 40 minutes. Interval session consists of warm-up, 8 reps/ four min (exercise: 2min, active
recovery: 2min, intensity: 90 /30) and cool down, but continues session includes 30 minutes of continuous
exercise intensity activity with 60% of peak oxygen consumption. The control group did not have a regular
activity. Blood samples taken before and after the eight-week and their P-selectin (by flow cytometry) and
platelet indices were measured. Repeated measure ANOVA with between group factor and multiple linear
regression were used for statistical analysis. The results showed that P-selectin expression changes between
the groups were significantly different (P=.013). Post-hoc test show that the changes between control and
interval groups were significant (P=.011). But no significant changes were observed in all platelet indices
(P>0.05).It is concluded that eight weeks of exercise leads to reduction in P-selectin expression that was also
affected by type of activity. Based on more effects of interval training in cardiovascular patients, use of
interval training can be suggested in their rehabilitation program.

Keywords

References

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Journal of Sport and Exercise Physiology
Volume 9, Issue 1 - Serial Number 17
March 2017
Pages 1355-1364

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History

  • Receive Date: 13 September 2016
  • Revise Date: 11 June 2024
  • Accept Date: 31 December 2020
  • First Publish Date: 31 December 2020
  • Publish Date: 21 May 2016

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