The Effect of Single session of Aerobic Interval Exercise on Serum Spexin Levels in Active Young Men

Document Type : original article

Abstract

Abstract
Aim: Spexin is a novel peptide which plays a role in the regulation of feeding behavior, body weight, energy metabolism, and long-chain fatty acid uptake into adipocytes. The aim of the current study was investigate the effect of single session of aerobic interval exercise on serum Spexin levels. Methods: Eleven active young men (aged 24±3.63 years, BMI 22.98±2 kg/m2) volunteered for this study. Acute exercise protocol comprising 2 series of 6×10 s sprinting cycling with maximal effort and 10 min active rest (cycling with intensity 65%–75% HRmax). Blood samples were obtained at fasting state, pre-exercise (30 min after breakfast ~365 kcal), immediately after, and 15, 30, and 45 min after exercise. The repeated measures of ANOVA and Bonferroni post-hoc test used to evaluate changes of parameters in the different times. The relationship between variables was assessed using the Pearson correlation coefficient. Results: Despite the changing levels of some metabolites such as glucose, insulin, lactate, TG and LDL-C in this study, spexin levels did not change significantly in any time courses of this study (p>0.05). At fasting state and post-exercise, spexin levels not correlated with other metabolites (p>0.05) but in 30 minutes after breakfast (pre-exercise) negatively correlated with TG (r= -0.645, p=0.032) and during the recovery period, positively correlated with HDL-C (r= +0.357, p=0.041) and negatively correlated with insulin (r= -0.672, p=0.023). Conclusion: It seems that acute exercise-induced negative energy balance in this study may not be sufficient to induce changes in Spexin serum levels.

Keywords

References

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History

  • Receive Date: 23 August 2016
  • Revise Date: 03 May 2024
  • Accept Date: 31 December 2020
  • First Publish Date: 31 December 2020
  • Publish Date: 22 May 2017

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