نوع مقاله : مقاله پژوهشی
نویسندگان
1 گروه فیزیولوژی ورزش، دانشکده علوم ورزشی، دانشگاه رازی، ایران.
2 گروه فیزیولوژی ورزش، دانشکده علوم ورزشی، دانشگاه رازی، کرمانشاه، ایران
3 فوق تخصص بیماریهای غدد درون ریز و دانشیار دانشگاه علوم پزشکی کرمانشاه
چکیده
کلیدواژه‌ها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
Introduction: People with metabolic diseases, especially those with type 2 diabetes, are more prone to developing dyslipidemia, which increases the risk of heart disease. Given the proven link between obesity, unhealthy lifestyle and chronic diseases, it is obvious that lifestyle modification - such as regular exercise and the use of nutritional supplements can be effective strategies for the prevention, management and treatment of obesity and its related disorders. The aim of the present study was to investigate the effects of 12 weeks of resistance training and curcumin supplementation on lipid profile, blood pressure and anthropometric indices in obese men with type 2 diabetes.
Methods: This study was conducted on 44 obese men (age 36.3±7.5 years; weight 86.42±5.28 kg; height 1.71±0.08 m) with a body mass index of more than 30 (kg/m2) and having type 2 diabetes. The subjects were randomly assigned to 4 groups of eleven: 1- Training+Curcumin (T+Cur), 2- Training+Placebo (T+P), 3- Supplement (Cur), 4- Placebo (P). The curcumin consuming groups (T+Cur and Cur) consumed one 500 mg capsule containing curcumin daily for twelve weeks. The P+T and T+Cur groups also performed 3 sessions per week of progressive resistance training at an intensity of 70-80% 1-RM for twelve weeks. Placebo groups (T+P and P) consumed the same curcumin capsules containing starch flour daily. Blood samples were taken before and 48 hours after the last exercise session, and also body composition, blood pressure, and resting heart rate were measured in this time points. Blood samples were used to measure lipid profile indices. Changes in pre- and post-exercise data were analyzed using one-way ANOVA, and if significant, Tukey's post-test was used to find the location of differences. Paired t-test was used to examine intra-group changes. Data analysis was performed using SPSS version 29 software, and the significance level was set at 0.05.
Results: One-way ANOVA results showed significant changes in HDL (P<0.001), LDL (P<0.001), triglycerides (TG) (P=0.005), and total cholesterol (TC) (P=0.004) in comparing different groups. Tukey's post hoc test results showed that the lipid profile changes were clearly greater in the T+Cur group than in the other intervention groups (P<0.05). Regarding the body composition data of body weight variables (P=0.031), body mass index (P<0.001), body fat percentage (P<0.001), waist-to-hip ratio (P<0.001), as well as systolic (P=0.002) and diastolic (P<0.001) blood pressure, the results of one-way ANOVA showed significant changes in the comparison of different groups. However, the data of resting heart rate did not show significant changes in the comparison of groups (P=0.474). In general, it was found that these improvements in all variables were greater in the T+Cur group compared to Cur and T alone.
Conclusion: According to the results of the present study, it can be concluded that curcumin supplementation along with resistance training can lead to further improvements in lipid profile, blood pressure, and body composition in obese men with type 2 diabetes. Therefore, these individuals can benefit from curcumin and foods containing it along with their exercise program to further benefit from the benefits of resistance training.
کلیدواژه‌ها [English]
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