نوع مقاله : مقاله پژوهشی
نویسندگان
1 گروه فیزیولوژی ورزشی، دانشکده علوم تربیتی و روانشناسی، دانشگاه شهید مدنی آذربایجان، تبریز، ایران
2 گروه فیزیولوژی ورزشی، دانشکده علوم تربیتی و روانشناسی، دانشگاه شهید مدنی آذربایجان، تبریز، ایران.
چکیده
کلیدواژه‌ها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
Abstract
Background and Objective: Type 2 diabetes is one of the most common metabolic disorders worldwide. Considering the complications and problems caused by diabetes, the use of herbal medicines can be a therapeutic and controlling method. Also, exercise is an important therapeutic component of type 2 diabetes. Given the limited information in these cases, the aim of the present study is to investigate the effect of 10 weeks of total body resistance training with chamomile extract supplementation on serum lipocalin-2 levels and glycemic indices in type 2 diabetic women.
Materials and Methods: For this purpose, in a double-blind clinical trial, 44 inactive diabetic women aged 40 to 60 years (mean height 159.45 cm, weight 76.83 kg, age 51.25 years, BMI 30.24 kg/m2) were voluntarily selected and randomly divided into four groups of 11 people each, including the exercise + supplement group (T + Cham), exercise + placebo group (T + P), chamomile group (Cham), and placebo group (P). The intervention consisted of 10 weeks of TRX training and 3 sessions per week (with a pressure intensity of 13 to 17 Borg). The supplement and placebo groups received 3 500 mg capsules daily containing chamomile extract and corn starch powder. Lipocalin 2, fasting blood sugar, insulin, and insulin resistance levels were measured before and after the intervention. Data were analyzed using ANOVA, Tukey's post hoc and paired t-tests at a significance level of P ≥ 0.05.
Findings: Blood glucose, insulin and insulin resistance index levels in all three study groups showed a significant decrease compared to the placebo group (P = 0.001). However, lipocalin 2 was significantly reduced only in the exercise+supplement and exercise+placebo groups compared to the placebo group (P = 0.001). Also, the exercise+supplement group had a significant difference in blood glucose, insulin and insulin resistance index variables compared to the exercise+placebo and chamomile groups (P ≤ 0.005). In addition, in the case of lipocalin-2, the exercise+supplement group had a significant difference compared to the chamomile group (P ≤ 0.005), but there was no significant difference compared to the exercise+placebo group.
Conclusion: According to the findings, it can be concluded that performing whole body resistance training with chamomile extract supplementation can reduce fasting blood sugar, insulin, insulin resistance, and lipocalin 2 levels in women with type 2 diabetes and be beneficial in improving women's health. Also, this intervention can be used as a complementary and non-pharmacological strategy in improving the condition of patients with type 2 diabetes.
Keywords: TRX, type 2 diabetes, chamomile extract, lipocalin 2, glycemic indices
کلیدواژه‌ها [English]
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