نوع مقاله : مقاله پژوهشی
عنوان مقاله English
نویسندگان English
### Background and Objective
Type 1 diabetes (T1D) is a chronic metabolic disorder characterized by impaired insulin secretion and is associated with adverse alterations in body composition, including increased fat mass and reduced fat-free mass, as well as disturbances in the lipid profile, such as elevated triglyceride and cholesterol levels. These metabolic alterations may increase the risk of cardiovascular complications. In children and adolescents with T1D, maintaining favorable body composition and lipid concentrations is therefore an important component of long-term disease management and cardiovascular risk reduction, alongside appropriate glycemic control. Regular physical activity may also contribute to improved metabolic regulation and healthier body composition in this population. The present study aimed to investigate the effects of vitamin D supplementation combined with aerobic exercise on body composition and lipid profile indices in children with type 1 diabetes.
### Materials and Methods
In this randomized controlled clinical trial, 48 children with type 1 diabetes, aged 9–11 years, residing in Kermanshah, Iran, were enrolled. Participants were randomly assigned to four groups (n=12 per group): vitamin D plus aerobic exercise (VitD+T), vitamin D alone (VitD), aerobic exercise plus placebo (P+T), and placebo (P). Participants in the vitamin D groups received one 1,000-IU vitamin D capsule daily for eight weeks. Participants in the exercise groups performed moderate-intensity aerobic exercise three sessions per week for eight weeks. Body composition and lipid profile indices were assessed in all participants before and after the intervention using standardized methods and instruments. Data were analyzed using IBM SPSS Statistics version 22, with statistical significance set at P
کلیدواژهها English
