اثیر تمرینات تناوبی پرشدت (HIIT) بر سطوح آیریزین و شاخص مقاومت انسولین در موش‌های صحرایی

نوع مقاله : علمی - پژوهشی

نویسندگان

1 داﻧﺸﮕﺎه ﺗﻬﺮان

2 داﻧﺸﮕﺎه زﻧﺠﺎن

چکیده

هدف: هدف از اجرای پژوهش، بررسی تاثیر 10 هفته تمرین اینتروال پرشدت را بر سطوح سرمی آیریزین و شاخص مقاومت انسولین (HOMA-IR) در موش‌های صحرایی نر بود. روش شناسی: 16 سر موش صحرایی نر نژاد ویستار به طور تصادفی به دو گروه کنترل (8 سر) و تمرینی (8 سر) تقسیم شدند. گروه تمرینی، تمرینات اینتروال پرشدت (یک دقیقه دوی سرعت و 2-5 دقیقه استراحت، 6-10 بار در روز، 5-6 روز در هفته، با سرعت 30-80 متر بر دقیقه) را به مدت 10 هفته، روی تردمیل اجرا کردند. 48 ساعت پس از آخرین جلسه تمرینی نمونه‌های خونی جمع‌اوری و سطوح سرمی آیریزین و انسولین به روش الایزا و سطوح گلوکز به روش گلوکز اکسیداز اندازه‌گیری شدند. تجزیه و تحلیل داده‌ها با آزمون آنالیز واریانس یک سویه و آزمون همبستگی پیرسون در سطح معنی‌داری 05/0>P انجام گرفت. نتایج: اجرای 10 هفته تمرینات تناوبی پرشدت افزایش معنی دار سطوح سرمی آیریزین (004/0=P) را در پی داشت. علاوه بر این در گروه تمرین سطوح گلوکز ناشتا و HOMA-IR کاهش یافت ولی این کاهش معنادار نبود(05/0<P)؛ سطوح انسولین سرمی در گروه تمرین بیش از گروه کنترل بود ولی این مقدار نیز معنی‌دار نبود(05/0<P). ضمناً رابطه‌ی معنی‌داری بین سطوح سرمی آیریزین با سطوح سرمی انسولین و شاخص مقاومت انسولین مشاهده نگردید ولی رابطه‌ی بین سطوح سرمی آیریزین با سطوح سرمی گلوکز معنی‌دار بود (029/0=P). بحث ونتیجه‌گیری: تمرینات اینتروال پر شدت سبب افزایش سطوح آیریزینی و بهبود شاخص مقاومت انسولینی در رت‌های نر می‌شود. 

کلیدواژه‌ها

عنوان مقاله [English]

Effect of High Intensity Interval Training (HIIT) on Level of Irisin and Insulin Resistance Index in Rats

چکیده [English]



Aims: The aim of this study was to investigate the effects of 10 week high intensity interval training on serum
levels of irisin and insulin resistance index (HOMA-IR) in male rats. Methodology: sixteen male wistar rats
were randomly divided in two control (n=8) and training (n=8) groups. Training group performed high
intensity interval training (1 min/sprint, 6~10 sets/day and 5~6 days/week) for 10 weeks. Blood samples were
collected 48 hours after last training session and serum levels of irisin, insulin and glucose were measured
using ELISA and glucose oxidase method. Statistical analysis was done by ANOVA and Pearson correlation
and (P<0.05) was considered significant. Results: serum levels of irisin (P=0.004) significantly increased
following 10 week high intensity interval training. In addition serum levels of fasting glucose and HOMA-IR
were decreased in the trained group but were not significant (P>0.05). Also serum levels of insulin in the
trained group were more than control group but were not significant (P>0.05). Hence there were not
significant correlations between irisin levels and insulin and HOMA-IR (P>0.05) but correlations between
irisin and glucose were not significant (P=0.029). Conclusion: high intensity interval training increases irisin
levels and improves insulin resistance index in male rats


کلیدواژه‌ها [English]

  • High Intensity Interval Training
  • Irisin
  • Insulin Resistance
  • Rat

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نشریه فیزیولوژی ورزش و فعالیت بدنی
دوره 8، شماره 1 - شماره پیاپی 15
اردیبهشت 1394
صفحه 1167-1174

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سابقه مقاله

  • تاریخ دریافت: 20 بهمن 1394
  • تاریخ بازنگری: 22 خرداد 1403
  • تاریخ پذیرش: 11 دی 1399
  • تاریخ اولین انتشار: 11 دی 1399
  • تاریخ انتشار: 01 اردیبهشت 1394

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