تاثیر 8 هفته فعالیت تناوبی با شدت بالا ی و تداومی بر سطح پایه بیانCD62Pو شاخص های پلاکتی در بیماران قلبی- عروقی

نوع مقاله : علمی - پژوهشی

نویسنده

دانشگاه شهید بهشتی

چکیده

هدف از این تحقیق مقایسه تاثیر 8 هفته فعالیت تناوبی با شدت بالا و تداومی بر سطح پایه بیان CD62Pو شاخص های پلاکتی در بیماران قلبی-عروقی بود. به همین منظور تعداد 30 بیمار قلبی CABG و PCI به صورت داوطلبانه انتخاب و در سه گروه 10 نفره کنترل، تمرین تداومی و تمرین تناوبی با شدت بالا تقسیم شدند. آزمودنی های دو گروه تمرین به مدت 8 هفته و هفته ای سه جلسه تمرین ورزشی داشتند. طول هر جلسه 40 دقیقه بود که فعالیت تناوبی شامل گرم کردن، 8 تکرار 4 دقیقه­ای فعالیت (2 دقیقه فعالیت و 2 دقیقه استراحت فعال باشدت 90 به30) و سرد کردن بود تمرین تداومی شامل 30 دقیقه فعالیت با شدت 60 درصد اوج اکسیژن مصرفی بود. گروه کنترل طی دوره تمرین هیچگونه فعالیت ورزشی نداشتند. نمونه های خونی قبل و بعد از هشت هفته گرفته شده و برای اندازه گیری پی سلکتین و شاخص های پلاکتی آنالیز شد. از تحلیل واریانس مکرر با عامل بین گروهی و رگرسیون خطی چندگانه برای تحلیل آماری داده ها استفاده شد. نتایج نشان داد بین تغییرات پی سلکتین در سه گروه تفاوت معنی دار وجود دارد (013/0=P). با مراجعه به آزمون تعقیبی مشاهده شد که بین تغییرات گروه کنترل و تمرین تناوبی تفاوت معتی داری وجود دارد (011/0=P). اما تغییرات شاخص های پلاکتی در سه گروه تفاوت معنی داری نشان نداد (05/0P>). براساس یافته های تحقیق حاضر می توان نتیجه گیری نمود که هشت هفته فعالیت ورزشی منجر به کاهش پی سلکتین می شود که این کاهش تحت تاثیر نوع فعالیت می باشد و با توجه به تاثیر بیشتر تمرین تناوبی در مقایسه با تمرین تداومی در بیماران قلبی-عروقی، می توان از تمرینات تناوبی نیز در برنامه بازتوانی این بیماران استفاده کرد.

عنوان مقاله [English]

Comparison the effects of 8 weeks of high intensity interval training and continuous trainingon CD62P expression and platelet indices in cardiovascular disease

چکیده [English]

The aim of this study was to compare the effects of 8 weeks of high intensity interval trainingandcontinuous training on CD62P expression and platelet indices in cardiovascular patients. Therefore, 30 CABG and PCI heart patient voluntary participated and divided into three groups (n=10): control, continuous and high-intensity interval group. Anthropometric characteristics and peak oxygen consumption was recorded before starting a workout. Each session was 40 minutes. Interval session consists of warm-up, 8 reps/ four min(exercise: 2min, active recovery: 2min, intensity: 90 /30) and cool down, but continues session includes 30 minutes of continuous exercise intensity activity with 60% of peak oxygen consumption. The control group did not have a regular activity. Blood samples taken before and after the eight-week and their p-selectin and platelet indices were measured. Repeated measure ANOVA with between group factor and multiple linear regression were used for statistical analysis. The results showed that P-selectin expression changes between the groups were significantly different (P=.013). Post-hoc test show that the changes between control and interval groups were significant (P=.011). But no significant changes were observed in all platelet indices (P>0.05).It is concluded that eight weeks of exercise leads to reduction in P-selectinexpression that was also affected by type of activity. Based on more effects of interval training in cardiovascular patients, use of interval training can be suggested in their rehabilitation program.

کلیدواژه‌ها [English]

  • P selectin-high intensity interval training-platelet indices-CABG-PCI
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