تأثیر هشت هفته تمرین در شرایط هایپوکسی و نورموکسی بر آیریزین و مقاومت به انسولین در مردان دارای اضافه‌وزن

[1] Kelly, T., et al., Global burden of obesity in 2005 and projections to 2030. International journal of obesity, 2008. 32(9): p. 1431-1437.
[2] Vinciguerra, F., et al., Very severely obese patients have a high prevalence of type 2 diabetes mellitus and cardiovascular disease. Acta diabetologica, 2013. 50(3): p. 443-449.
[3] Nishida, T., et al., Oral glucose tolerance test predicts prognosis of patients with liver cirrhosis. The American journal of gastroenterology, 2006. 101(1): p. 70-75.
[4] Grundy, S.M., et al., Transport of very low density lipoprotein triglycerides in varying degrees of obesity and hypertriglyceridemia. The Journal of clinical investigation, 1979. 63(6): p. 1274-1283.
[5] Lewis, G.F. and G. Steiner, Acute effects of insulin in the control of VLDL production in humans: implications for the insulin- resistant state. Diabetes care, 1996. 19(4): p. 390-393.
[6] Rector, R.S., et al., Daily exercise increases hepatic fatty acid oxidation and prevents steatosis in Otsuka Long-Evans Tokushima Fatty rats. American Journal of Physiology- Gastrointestinal and Liver Physiology, 2008. 294(3): p. G619-G626.
[7] Woods, S.C., et al., Regulation of energy homeostasis by peripheral signals. Best Practice & Research Clinical Endocrinology & Metabolism, 2004. 18(4): p. 497-515.
[8] Boström, P., et al., A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature, 2012. 481(7382): p. 463.
[9] Cinti, S., Between brown and white: novel aspects of adipocyte differentiation. Annals of medicine, 2011. 43(2): p. 104-115.
[10] Shifren, J.L., et al., In the human fetus, vascular endothelial growth factor is expressed in epithelial cells and myocytes, but not vascular endothelium: implications for mode of action. The Journal of Clinical Endocrinology & Metabolism, 1994. 79(1): p. 316-322.
[11] Mazzeo, R.S., et al., Interleukin-6 response to exercise and high-altitude exposure: influence of α-adrenergic blockade. Journal of Applied Physiology, 2001. 91(5): p. 2143-2149.
[12] Chen, C.-Y., et al., Effect of mild intermittent hypoxia on glucose tolerance, muscle morphology and AMPK-PGC- 1alpha signaling. Chin J Physiol, 2010. 53(1): p. 62-71.
[13] Akira, S., IL-6 and NF-IL6 in acute-phase response and viral infection. Immunological reviews, 1992. 127(1): p. 25-50.
[14] Benso, A., et al., Endocrine and metabolic responses to extreme altitude and physical exercise in climbers. European Journal of Endocrinology, 2007. 157(6): p. 733-740.
[15] Zhigang Li, X.W., Xue Song,Fangfang Zhao, Hao Chen, Wengtao Lin., Hypoxic Training Increases the Concentration of Serum Irisin and Reduces. Weight in Diet-induced Obese Rats. Biological Conservation, 2018. 3(2): p. 18-23.
[16] Zebrowska, A., et al., Moderate intensity exercise in hypoxia increases IGF-1 bioavailability and serum irisin in individuals with type 1 diabetes. Ther Adv Endocrinol Metab, 2020. 11: p. 2042018820925326.
[17] Quintero, P., et al., Impact of oxygen availability on body weight management. Medical hypotheses, 2010. 74(5): p.
901-907.
[18] Morton, J.P. and N.T. Cable, The effects of intermittent hypoxic training on aerobic and anaerobic performance. Ergonomics, 2005. 48(11-14): p. 1535-1546.
[19] Matthews, D., et al., Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia, 1985. 28(7): p. 412-419.
[20] Raff, H., Total and active ghrelin in developing rats during hypoxia. Endocrine, 2003. 21(2): p. 159-161.
[21] Soori, R., et al., The effect of aerobic training on the serum level of adipolin and insulin resistance in overweight men. Feyz Journal of Kashan University of Medical Sciences, 2016. 19.
[22] Azali Alamdari, K. and H. Rohani, Effects of normobaric and hypobaric endurance training on metabolic risk factors in midlife men. Iranian Journal of Endocrinology and Metabolism, 2015. 17(2): p. 113-123.
[23] Khodadadi, H., et al., The effect of high intensity interval training (HIIT) and pilates on levels of irisin and insulin resistance in overweight women. Iranian Journal of Endocrinology and Metabolism, 2014. 16(3): p. 190-196.
[24] Daskalopoulou, S.S., et al., Plasma irisin levels progressively increase in response to increasing exercise workloads in young, healthy, active subjects. European journal of endocrinology, 2014. 171(3): p. 343-352.
[25] Puigserver, P., et al., A cold-inducible coactivator of nuclear eceptors linked to adaptive the rmogenesis. Cell, 1998.92(6): p. 829-839.
[26] Boström, P., et al., A PGC1-[agr]-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature, 2012. 481(7382): p. 463-468.
[27] Polyzos, S.A., et al., Irisin: a renaissance in metabolism? Metabolism-Clinical and Experimental, 2013. 62(8): p. 1037-1044.
[28] Shimoda, L.A. and G.L. Semenza, HIF and the lung: role of hypoxia-inducible factors in pulmonary development and disease. American journal of respiratory and critical care medicine, 2011. 183(2): p. 152-156.
[29] Norheim, F., et al., The effects of acute and chronic exercise on PGC-1α, irisin and browning of subcutaneous adipose tissue in humans. The FEBS journal, 2014. 281(3): p. 739-749.
[30] Huh, J.Y., et al., Irisin in response to exercise in humans with and without metabolic syndrome. The Journal of Clinical Endocrinology & Metabolism, 2015. 100(3): p. E453-E457.
[31] Chaiban, J.T., F.F. Bitar, and S.T. Azar, Effect of chronic hypoxia on leptin, insulin, adiponectin, and ghrelin. Metabolism, 2008. 57(8): p. 1019-1022.
[32] Domenici, P., et al., The effect of hypoxia on fish swimming performance and behaviour, in Swimming physiology of fish. 2013, Springer. p. 129-159.
[33] Cuff, D.J., et al., Effective exercise modality to reduce insulin resistance in women with type 2 diabetes. Diabetes care, 2003. 26(11): p. 2977-2982.
[34] Afshon Pour, M., A. Habibi, and R. Ranjbar, Effects ofContinuous Aerobic Exercise Training on Plasma Concentration of Apelin and Insulin Resistance in Type 2 Diabetic Men. Armaghane danesh, 2016. 21(1): p. 57-70.