تأثیر شدت‌های مختلف تمرین مقاومتی دایره‌ای بر گرملین-1، عامل بازدارندة مهاجرت ماکروفاژها و برخی شاخص‌های خطرزای قلبی -عروقی در مردان چاق

نوع مقاله : علمی - پژوهشی

نویسندگان

1 گروه فیزیولوژی ورزشی، واحد آیت الله آملی، دانشگاه آزاد اسلامی، آمل، ایران

2 گروه فیزیولوژی ورزشی، واحد آیت‌الله آملی، دانشگاه آزاد اسلامی، آمل، ایران

3 گروه تربیت بدنی و علوم ورزشی، دانشکدة ادبیات و علوم انسانی، دانشگاه کردستان، سنندج، کردستان، ایران

چکیده

زمینه و هدف: بافت چربی بیشتر در پی چاقی، با افزایش نشانگرهای التهابی همراه است. هدف از این پژوهش، بررسی تأثیر شدت‌های مختلف تمرین مقاومتی دایره‌ای بر گرملین-1، عامل بازدارندة مهاجرت ماکروفاژها و برخی شاخص‌های خطرزای قلبی- عروقی در مردان چاق بود.  
مواد و روش‌ها: در یک کارآزمایی نیمه‌تجربی، 44 مرد چاق انتخاب و به‌صورت تصادفی به چهار گروه کنترل (11 نفر)، تمرین مقاومتی دایره‌ای با شدت پایین (11 نفر)، تمرین مقاومتی دایره‌ای با شدت متوسط (11 نفر) و تمرین مقاومتی دایره‌ای با شدت بالا (11 نفر) تقسیم شدند. تمرین مقاومتی با شدت‌های مختلف شامل تمرین دایره‌ای با شدت بالا (80 درصد 1RM)، تمرین دایره‌ای با شدت متوسط (60 درصد 1RM) و تمرین دایره‌ای با شدت پایین (40 درصد 1RM)، سه جلسه در هفته و به مدت 12 هفته بود. سطوح گرملین-1، MIF و نیمرخ لیپیدی (کلسترول، تری‌گلیسرید، LDL و HDL) سرم با استفاده از کیت و به روش الایزا اندازه‌گیری شد. داده‌ها به روش آزمون تحلیل واریانس با اندازه‌گیری مکرر، آزمون تی وابسته و آزمون تعقیبی بونفرونی در سطح معناداری 05/0 P< تجزیه‌وتحلیل شد.
نتایج: 12هفته تمرین مقاومتی دایره‌ای با شدت پایین، متوسط و بالا موجب کاهش معنادار با کاهش معنادار سطوح گرملین1 و MIF، کاهش معنادار سطوح کلسترول، تری‌گلیسرید و LDL-c و افزایش معنادار سطوح HDL-c شد (001/0=P).
نتیجه‌گیری: به‌نظر می‌رسد تمرین مقاومتی دایره‌ای با شدت‌های مختلف و به‌ویژه شدت بالا می‌تواند عامل مؤثری به‌منظور مقابله با افزایش مشاهده در عوامل خطرزای قلبی-عروقی در افراد چاق باشد.

کلیدواژه‌ها

عنوان مقاله [English]

The effect of different intensity circuit resistance training on gremlin-1, Macrophage migration inhibitory factor and some cardiovascular risk factors in obese men

نویسندگان [English]

  • Mohammad Karami 1
  • Asieh Abbassi Daloii 2
  • Ayoub Saeidi 3
1 Department of Exercise Physiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
2 Department of Exercise Physiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
3 2Department of Physical Education and Sport Sciences, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj, Kurdistan, Iran
چکیده [English]

Background and Purpose: More Adipose tissue is associated with the increase of inflammatory markers in obesity. This study aimed to evaluate the effect of different intensity circuit resistance training on gremlin-1, Macrophage migration inhibitory factor and some cardiovascular risk factors in obese men.
Materials and Methods: In a semi-experimental trial, 44 obese men were selected and randomly divided into four groups including control (n=11), low intensity circuit resistance training (n=11), moderate intensity circuit resistance training (n=11) and high-intensity circuit resistance training (n=11) groups. Resistance training was performed in different intensities included 1) High-intensity circuit resistance training (80% 1RM) 2) Moderate intensity circuit resistance (60% 1RM) and 3) Low intensity circuit resistance training (40% 1RM), three sessions per week for 12 weeks. Serum levels of gremlin-1, MIFand Lipid profile (cholesterol, triglyceride, LDL and HDL) were measured using kit and ELISA method. Data were analyzed with Analysis of variance with repeated measures, dependent t-test and Bonferroni post hoc test at the P < 0.05.
Results:12 weeks of circular resistance training with low, moderate and high intensity caused a significant decrease in gremlin-1 and MIF levels, significant decrease in cholesterol, triglyceride and LDL-c levels and significant increase in HDL-c levels (P = 0.001).
Conclusion: It seems that circular resistance training with different intensities and especially high intensity can be an effective factor in counteracting the increase in observation of cardiovascular risk factors in obese people.

کلیدواژه‌ها [English]

  • Circuit resistance training
  • Obesity
  • Macrophage migration inhibitory factor
  • Gremlin-1
  • Lipid profile

مراجع

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سابقه مقاله

  • تاریخ دریافت: 25 دی 1399
  • تاریخ بازنگری: 04 مهر 1400
  • تاریخ پذیرش: 24 مهر 1400
  • تاریخ اولین انتشار: 29 خرداد 1401
  • تاریخ انتشار: 01 تیر 1401

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