تأثیر شش هفته تمرینات ترکیبی بر سطح استراحتی پنتراکسین3 و سرم آمیلوئید A پلاسمای مردان مبتلا به دیابت نوع دو

حقگو, حمیدرضا; چوبینه, سیروس; پورنعمتی, پریسا

doi:10.52547/joeppa.15.4.1

تأثیر شش هفته تمرینات ترکیبی بر سطح استراحتی پنتراکسین3 و سرم آمیلوئید A پلاسمای مردان مبتلا به دیابت نوع دو

نوع مقاله : علمی - پژوهشی

نویسندگان

گروه فیزیولوژی ورزش، دانشکدة تربیت بدنی و علوم ورزشی، دانشگاه تهران، تهران، ایران

10.52547/joeppa.15.4.1

چکیده

زمینه و هدف: هدف از پژوهش حاضر بررسی تأثیر تمرینات ترکیبی بر سطح استراحتی پنتراکسین3 (PTX3) و سرم آمیلوئید A(SAA) پلاسمای مردان مبتلا به دیابت نوع دو بود تا بدین‌وسیله، تأثیر ورزش بر کاهش عوامل التهابی فوق در افراد دیابتی سنجیده شود.
مواد و روش‌ها: ۲۰ مرد غیرورزشکار مبتلا به دیابت نوع دو، تصادفی در دو گروه کنترل و تمرین توزیع شدند. تمرینات ترکیبی به مدت شش هفته شامل 25-35 دقیقه تمرین هوازی با شدت 55-75 درصد ضربان قلب بیشینه و پنج حرکت مقاومتی دربرگیرندة عضلات بزرگ بالا و پایین‌تنه شامل پنج حرکت پرس سینه، پرس ارتشی، اسکات، لیفت مرده، حرکت پارویی دمبل با شدت 55-75 درصد یک تکرار بیشینه با تواتر سه بار در هفته با تقدم تمرینات مقاومتی بر هوازی در هر جلسه برگزار شد. شدت تمرینات هوازی با ساعت ضربان‌سنج و شدت تمرینات مقاومتی نیز هر دو هفته یک‌بار با آزمون یک تکرار بیشینه سنجیده شد. تجزیه‌وتحلیل داده‌ها با استفاده از آزمون تی وابسته و تی ‌مستقل در سطح معناداری 05/0‌P≤ انجام گرفت.
نتایج: با بررسی نتایج پژوهش مشخص شد قرارداد تمرینی، سبب کاهش شاخص SAA (7/16درصد) و تغییر معنادار آن در گروه تمرین نسبت به گروه کنترل شد (047/0P=)، این در حالی است که تأثیری بر میزان SAA استراحتی گروه کنترل نداشت و افزایش 2/2 درصدی PTX3 گروه تمرین معنادار نبود (474/0=P).
نتیجه‌گیری: با توجه‌ به نتایج پژوهش و کاهش معنادار در عامل التهابی SAA و افزایش PTX3 می‌توان نتیجه گرفت که شش هفته تمرینات ترکیبی بر سطوح عوامل ذکرشده در مردان مبتلا به دیابت نوع دو تأثیرگذار است و احتمالاً می‌تواند سبب کاهش التهاب در این بیماران شود.

کلیدواژه‌ها

عنوان مقاله [English]

The effect of six weeks of combined training on the resting plasma level of Pentraxin-3 and Serum amyloid A in men with type-2 diabetes

نویسندگان [English]

Hamidreza Haghgoo
Siroos Choobineh
Parisa Pournemati

Department of Exercise Physiology , Faculty of Physical Education and Sport Sciences , University of Tehran, Tehran , Iran

چکیده [English]

Background and Purpose: The aim of this study was to investigate the effect of combined exercise on resting levels of pentraxin3 (PTX3) and serum amyloid A (SAA) in the plasma of men with type-2 diabetes.
Materials and Methods: Twenty oen-athlete men with type-2 diabetes were randomly divided into control and training groups. Combined training was performed for six weeks. Training including 25-35 minutes of aerobic exercise with an intensity of 55-75% of maximum heart rate and five resistance movements involving large muscles in the upper and lower body Includes five movements: chest press, army press, squat, dead lift, dumbbell rowing with an intensity of 55-75% of a maximum repetition with a frequency of three times a week with the periorizing of resistance training on aerobic training . The intensity of aerobic exercise was measured with heart rate monitor and the intensity of resistance training was measured every two weeks with a maximum repetition test. For data analysis, dependent and independent t-test was used at the significant level of P ≤ 0.05.
Results: Examining the results of the study, it was found that the training contract reduced the SAA index (16.7%) and significantly changed it in the training group compared to the control group (P = 0.047 . However, there was no effect on resting SAA in the control group and a 2.2% increase in PTX3 in the training group was not significant (P = 0.474).
Conclusion: According to the results of the study and a significant decrease in inflammatory factor SAA and increase in PTX3, it can be concluded that six weeks of combined training affects the levels of these factors in men with type-2 diabetes and can probably reduce inflammation in these patients.

کلیدواژه‌ها [English]

Diabetes Mellitus
Type 2 - PTX3 protein
Serum Amyloid A Protein
Inflammation
Resistance Training

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