اثر هشت هفته تمرین استقامتی بر کلاژن 18 پلاسمایی و عضله قلبی موشهای صحرایی نر ویستار

نوع مقاله : علمی - پژوهشی

نویسندگان

1 دانشگاه آزاد اسلامی

2 دانشگاه شهید بهشتی

چکیده

چکیدههدف: هدف از این پژوهش بررسی اثر یک دوره تمرین استقامتی بر کلاژن 18 پلاسمایی و عضله قلبی موشهای نر ویستار بود.و تمرین (C) 135 گرم) به طور تصادفی به دو گروه کنترل - 6 هفتهای و 125 - روش شناسی: 16 سر موش صحرایی نر ویستار ( 4تقسیم شدند. برنامه تمرینی شامل 8 هفته، 5 روز در هفته، به مدت 20 تا 60 دقیقه و سرعت 28 تا 34 متر در دقیقه بود. (T)72 ساعت پس از آخرین جلسه تمرینی نمونهگیری خون و بافت برداری انجام شد. مقدار کلاژن 18 به روش الایزا اندازهگیری شد.تجزیه و تحلیل شد. نتایج: مقدار کلاژن 18 پلاسمایی α<0/ مستقل در سطح معنیداری 05 t دادهها با استفاده ازپس از هشت هفته فعالیت (T=40/476±11/933 ،C=20/080±3/ و عضله قلبی ( 169 (T=0/839±0/079 ،C=0/721±0/142)بحث و نتیجهگیری: افزایش کلاژن .( P=0/ ورزشی افزایش داشت، ولی این افزایش فقط در سطح عضله قلبی معنیدار بود ( 04618 احتمالاً نشان دهنده تأثیر فعالیتهای ورزشی بر مهار رگزایی بوده و گواه دیگری بر اثرات ضد سرطانی فعالیتهای ورزشیمیباشد.

کلیدواژه‌ها

عنوان مقاله [English]

Effect of 8 week endurance training on plasma and heart tissue collagen XVIII in male Wistar rats

چکیده [English]

 
Purpose: the aim of this study was to examine the effect of endurance training on plasma and heart tissue collagen XVII in male Wistar rats. Methods: 16 male Wistar rats (4-6 week old. 125-135 g weight) were randomly divided two groups: experimental (n=8) and control (n=8) groups. Training protocol consisted of treadmill exercise at 20 to 60 min, speed 28 to 34 m٫min. (0%) grade, for 5days٫week for 8 weeks. Rats were sacrificed 72 h after the last session of exercise for measurement collagen XVIII levels in plasma and heart tissue. Plasma and tissue collagen XVIII levels measured using ELISA. Data were analyzed using independent t-test at P= 0.05. Results collagen XVIII levels increased in plasma and heart tissue after 8 weeks endurance training, but significant difference observed only in heart tissue (P=0.046). Conclusion: It likely appears that increased of collagen XVIII was indicator of exercise training effect on anti-angiogenesis and confirmed the anti-cancer impact of exercise training.
 

کلیدواژه‌ها [English]

  • endurance training
  • collagen XVIII plasma and heart tissue
  • male Wistar rats

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سابقه مقاله

  • تاریخ دریافت: 11 خرداد 1394
  • تاریخ بازنگری: 29 خرداد 1403
  • تاریخ پذیرش: 11 دی 1399
  • تاریخ اولین انتشار: 11 دی 1399
  • تاریخ انتشار: 01 مهر 1391

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