اثر 6 هفته تمرین تای‌چی بر سطوح سرمیTNF-α، BDNFو عملکرد شناختی و جسمانی زنان با عارضه سکته مغزی

نوع مقاله : علمی - پژوهشی

نویسندگان

دانشکده تربیت بدنی دانشگاه خوارزمی تهران

چکیده

هدف: هدف از پژوهش حاضر تعیین اثر 6 هفته تمرین تای‌چی بر مقادیر سرمی TNF-α،BDNF و عملکرد شناختی و جسمانی زنان با عارضه سکته مغزی بود. روش‌شناسی: 20 نفر از زنان شهر قم با عارضه سکته مغزی(میانگین سن55/3±80/65سال، وزن00/14±41/68 کیلوگرم و شاخص توده بدنی 15/5±33/26 کیلوگرم بر مترمربع) به صورت داوطلبانه انتخاب و به طور تصادفی به دو گروه تجربی(10 نفر) و کنترل(10 نفر) تقسیم شدند. مقادیر سرمی TNF-α و BDNF با استفاده از روش الایزا در پیش آزمون و پس آزمون مشخص شد. همچنین جهت ارزیابی تعادل پویا و عملکرد شناختی، به ترتیب از آزمون مدت زمان برخاستن و رفتن (TUG) و پرسشنامه معاینه مختصر وضعیت شناختی استفاده شد. آزمودنی‌های گروه تجربی به مدت 6 هفته، هر هفته 3 جلسه و به مدت 60 دقیقه(شامل 10 دقیقه گرم کردن، 40 دقیقه حرکات ساده شده تمرینات تای‌چی و 10 دقیقه بازگشت به حالت اولیه) تمرین کردند. تجزیه و تحلیل داده‌ها با استفاده از آزمون‌های T وابسته و T مستقل انجام گرفت. نتایج: نتایح پژوهش حاضر نشان داد که مقادیر TNF-α کاهش معناداری نسبت به گروه کنترل یافت. همچنین تعادل پویای گروه تمرین تای‌چی نسبت به گروه کنترل بهبود معناداری یافت(P<0/05). اما با وجود افزایش مقادیر BDNF و بهبود عملکرد شناختی تفاوت معناداری بین دو گروه مشاهده نشد. نتیجه‌گیری: یافته‌های پژوهش حاضر پیشنهاد می‌کند که تمرین تای‌چی بعنوان تمرین کم شدت و ساده می‌تواند باعث بهبود تعادل و وضعیت التهابی زنان با عارضه سکته مغزی شود.

عنوان مقاله [English]

The effect of 6 weeks Tai chi training on TNF-α, BDNF serum levels and cognitive and physical function in women with stroke

چکیده [English]

The aim of this study was to determine the effect of Tai Chi training on TNF-α, BDNF serum levels and cognitive and physical function in women with stroke. 20 women in Qom city with stroke (mean age: 68/80±3/55y, weight: 68/41±14/00 kg and body mass index: 26/33± 5/15kg/m2) voluntarily were divided randomly into Tai Chi group (10 patients) and control group (10 patients). Serum BDNF and TNF-α were analyzed by using an ELISA kits in pretest and post-test. Cognitive function were assessed by the Mini-Mental State Examination (MMSE). Also pretest and post-test measurements were recorded for the timed up-and-go test. Tai Chi group trained 6 weeks, three times per week for 60 minute(consisted of a 10-minute warm-up period, 40-minutes simplified Tai Chi exercises performed, and a 10-minute cool-down period). Data were analyzed using the independent samples T-test and paired samples T-test. Tai Chi group showed a significant improvement in serum TNF-α and dynamic balance (p≤0.05). Despite the increase in serum BDNF and improvement cognitive function, no significant differences were observed between the two groups. Therefore the findings of this study suggest that Tai Chi training as a low intensity and simple training can improve women balance and inflammatory status with stroke.

کلیدواژه‌ها [English]

  • Tai Chi training-BDNF-TNF-α-Cognitive status- Dynamic balance- Stroke
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