نوع مقاله : علمی - پژوهشی
نویسنده
دانشکده تربیت بدنی و علوم ورزشی، دانشگاه عالمه طباطبائی، تهران، ایران
چکیده
هدف: این تحقیق برای تعیین پاسخهای متابولیکی به تزریق گلوکز )هایپرگلیسمی( طی فعالیت ورزشی در مردان سالمند طراحی
شد.
روشها: هشت مرد سالم )میانگین سن 2/5±3/63 سال( داوطلبانه در این تحقیق شرکت کردند و در دو جلسه مجزا به فاصله
یک هفته به آزمایشگاه فیزیولوژی مراجعه کردند. آزمودنیها در هر جلسه 40 دقیقه فعالیت ورزشی روی دوچرخه با 60 درصد
حداکثر اکسیژن مصرفی بعد از 30 دقیقه تزریق گلوکز یا دارونما اجرا کردند. گازهای تنفسی طی فعالیت اندازهگیری شدند و 4
نمونه خونی قبل از تزریق گلوکز، بعد از اتمام 30 دقیقه تزریق گلوکز، در دقیقه 20 فعالیت، و سریعا بعد از اتمام فعالیت برای
اندازهگیری فاکتورهای متابولیکی، گرفته شدند. نمونههای خونی برای اندازهگیری انسولین، اسید چرب آزاد استریفیهنشده،
گلیسرول، بتاهیدروکسی بوتیرات (OHB-3 (و مقاومت به انسولین (HOMA (استفاده شدند. اکسیداسیون چربی و کربوهیدرات با
استفاده ار گازهای تنفسی دیاکسید کربن و اکسیژن مصرفی محاسبه شد.
نتایج: آنالیز آماری دادهها افزایش معنادار )05/P0 )انسولین و گلوکزو کاهش اسید چرب آزاد غیراستریفیه و گلیسرول را طی
فعالیت ورزشی بعد از تزریق گلوکز نشان داد اما تاثیر معناداری بر سوخت چربی و کربوهیدرات مشاهده نشد.
نتیجهگیری: بر اساس یافتههای این تحقیق میتوان نتیجهگیری کرد که در مردان سالمند حفظ سطح گلوکز خون حین فعالیت
ورزشی از طریق تزریق گلوکز بر لیپولیز و عوامل متابولیکی تاثیر دارد اما بر اکسیداسیون چربی و کربوهیدرات در عضله تاثیر ندارد.
کلیدواژه‌ها
عنوان مقاله [English]
Metabolic responses to hyperglycaemia during exercise in elderly men
نویسنده [English]
- Minoo Bassami
Faculty of physical education and sports sciences, Allameh Tabataba'i University, Tehran, Iran
چکیده [English]
Purpose: The present study was designed to determine the metabolic responses to hyperglycaemia during
exercise in elderly men.
Methods: Eight healthy males (Age, 63.3±5.2 years) voluntarily participated and reported to the physiology
laboratory on two separate occasions. With one week intervening subjects performed 40 min exercise on a
cycle ergometer at 60% VO2max after 30 minutes of ‘prime’ glucose or placebo infusion. Respiratory gases
were undertaken throughout the exercise and four blood samples were taken before infusion, after 30 min
infusion, after 20 min exercise and immediately after exercise. Blood samples were analyzed to determine
insulin, NEFA, glycerol, 3- OHB and HOMA Scores. Fat and carbohydrate oxidation were calculated by using
respiratory gases of O2 and CO2.
Results: Insulin and glucose concentrations were significantly (p<0.05) higher, and NEFA and glycerol were
lower during exercise after glucose infusion. However, 3-OHB, fat and carbohydrate oxidations were not
significantly different between two trials (p>0.05).
Conclusions: Based on the findings of the present study it could be concluded that in elderly men the
maintenance of blood glucose during exercise through glucose infusion affects on lipolysis and metabolic
factors, but has no effect on muscular fat and carbohydrate oxidation.
کلیدواژه‌ها [English]
- Cycling: Cycling
- Fat oxidation
- Carbohydrate oxidation
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