پاسخهای متابولیکی به هایپرگلیسمی طی فعالیت ورزشی در مردان سالمند

نوع مقاله : علمی - پژوهشی

نویسنده

علامه طباطبائی

چکیده

مقدمه تحقیق حاضر جهت تعیین پاسخ های متابولیکی به تزریق گلوکز (هایپرگلیسیمیا) طی فعالیت ورزشی در  مردان مسن طراحی گردید. مواد و روش‌ها:  هشت مرد سالم (میانگین سن 2/5±3/63 سال) بطور داوطلبانه در این تحقیق و در دو جلسه مجزا به فاصله یک هفته به آزمایشگاه فیزیولوژی مراجعه کردند. آزمودنی ها در هر جلسه 40 دقیقه فعالیت ورزشی بر روی دوچرخه با 60 درصد حداکثر اکسیژن مصرفی  بعد از 30 دقیقه تزریق گلوکز یا دارونما اجرا کردند. فاکتورهای تنفسی در طی فعالیت اندازه گیری شدند و 4 نمونه خونی قبل از تزریق گلوکز، بعد از اتمام 30 دقیقه ترزیق گلوکز، در دقیقه 20 فعالیت، و سریعا بعد از اتمام فعالیت برای اندازه گیری فاکتورهای متابولیکی، گرفته شد. اکسیداسیون چربی و کربوهیدرات با استفاده ار گازهای تنفسی دیاکسید کربن و اکسیژن مصرفی محاسبه گردید. یافته‌ها: آنالیز آماری داده ها افزایش معنی دار (p<0.05) انسولین و گلوکز و کاهش اسید چرب آزاد غیراستریفیه و گلیسرول را طی فعالیت ورزشی بعد از تزریق گلوکز نشان داد اما تاثیر معنی داری بر سوخت چربی و کربوهیدرات مشاهده نگردید. نتیجه گیری: اگر چه تحقیقات قبلی بر روی جوانان نشان داده اند که سوخت چربی و کربوهیدرات بعد از تزریق گلوکز تغییر پیدا کرده است. اما در تحقیق حاضر در مردان مسن علیرغم تغییرات متابولیکی در طی فعالیت ورزشی بعد از تزریق گلوکز، اکسیداسیون چربی و کربوهیدرات تغییر معنی داری نداشت.

عنوان مقاله [English]

Hormonal and metabolic responses to hyperglycaemia during exercise in elderly men

نویسنده [English]

  • Minoo Bassami
Faculty of physical education and sports sciences, Allameh Tabataba'i University
چکیده [English]

Introduction: The present study was designed to determine the metabolic responses to hyperglycaemia during exercise in elderly men. Methods: Eight healthy males (Age, 63.3±5.2 years) voluntarily participated and reported to the physiology laboratory on two separate occasions. With one week intervening subjects performed 40 min exercise on a cycle ergometer at 60% after 30 minutes of ‘prime’ glucose or placebo infusion. Respiratory measures were undertaken throughout the exercise and four blood samples were taken before infusion, after 30 min infusion, after 20 min exercise and immediately after exercise. Blood samples were analyzed to determine insulin, NEFA, glycerol, 3- OHB and H0MA Scores. Fat and carbohydrate oxidation were calculated by using respiratory gases of O2 and CO2. Results: Insulin and glucose concentrations were significantly (p

کلیدواژه‌ها [English]

  • Cycling- hyperglycaemia- fat oxidation- carbohydrate oxidation- elderly
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