اثر هشت هفته تمرین هوازی متوسط بر فشار خون، سطوح سرمی نیتریک اکساید و آپلین زنان میانسال مبتلا به پیش فشار خونی

نوع مقاله : علمی - پژوهشی

نویسندگان

1 دانشگاه آزاد کرمانشاه

2 دانشگاه رازی کرمانشاه

چکیده

هدف: فشارخون تحت تاثیر عوامل مختلفی از جمله فعالیت قرار می­گیرد هدف از مطالعه حاضر بررسی اثر هشت هفته تمرین هوازی بر فشارخون، نیتریک اکساید و آپلین در زنان مبتلا به پیش پرفشاری خون بود. روش شناسی: 24 زن 45-30 ساله مبتلا به پیش پرفشاری خون به طور تصادفی به دو گروه هوازی و کنترل تقسیم شدند. تمرین هوازی سه بار در هفته، به مدت هشت هفته بود، به این صورت که آزمودنی­ها هفته اول به مدت 30 دقیقه با 50 درصد ضربان قلب ذخیره، هفته دوم و سوم به ترتیب مدت 35 و 40دقیقه با شدت 50 درصد، هفته چهارم مدت 40 دقیقه و شدت 55 درصد و هفته های پنجم، ششم، هفتم و هشتم  به مدت 45 دقیقه با شدت 55 درصد ضربان قلب ذخیره دویدند. اندازه گیری فشارخون و نمونه گیری خون یک روز پیش از نخستین وهله و 48 ساعت پس از آخرین وهله تمرین انجام شد. سطوح آپلین و نیتریک اکساید با استفاده از کیت­های تجاری به روش الایزا اندازه گیری شدند، تجزیه و تحلیل آماری داده ها با استفاده از آزمون تی مستقل و وابسته در سطح معناداری (0.05>p) صورت گرفت. نتایج: پس از 8 هفته فعالیت هوازی سطوح آپلین و نیتریک اکساید در گروه تمرین افزایش معناداری داشتند (0.05>p). در صورتی که سطح فشارخون کاهش معناداری داشت (0.05>p). بحث و نتیجه گیری: 8 هفته تمرین هوازی می­تواند از طریق افزایش سطوح نیتریک اکساید و آپلین و کاهش سطح فشارخون برای افراد مبتلا به پیش پر فشاری خون مفید باشد.

عنوان مقاله [English]

Effect of eight weeks aerobic training on nitric oxide and apelin levels in women with pre-hypertension

نویسندگان [English]

  • leila hojatoleslami 1
  • vahid tadibi 2
  • naser behpoor 2
1 Kermanshah Azad University
2 Razi University of Kermanshah
چکیده [English]

purpose: Blood pressure is affected by various factors including activity. The aim of this study was to investigate the effect of eight weeks of aerobic training on blood pressure, nitric oxide and apelin in women with pre-hypertension. Methods: Twenty-four women aged 30-45 years with pre-hypertension were randomly divided in two groups: aerobic and control. Aerobic exercise was performed three times a week for eight weeks, This means that subjects the first week for 30 minutes at 50% heart rate reserve, the second and third weeks respectively were 35 and 40 minutes with a 50% intensity, Fourth week 40 minutes and intensity 55%, and 5th, 6th, 7th and 8th weeks run For a period 45 minutes with 55% heart rate reserve. Blood pressure measurement and blood sampling were performed one day before the first and 48 hours after the last exercise. Apelin and nitric oxide levels were measured using commercial kits by ELISA method. Statistical analysis of data was performed using independent and dependent t-test at a significant level (p

کلیدواژه‌ها [English]

  • Prehypertension
  • Aerobic exercise
  • nitric oxide
  • Apelin
  • Endothelial function
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